View By Date

Statistics

  • 254557
    Blogs
  • 54741
    Active Bloggers
31682 blogs
  • 26 Sep 2018
    SPORTS INJURIES, ACCIDENTS, and tooth decay are just a few of the reasons we might lose a tooth. Thanks to modern dentistry, however, we don’t need to settle for having a gap in our smiles for the rest of our lives. There are a few ways to fill that gap, and one of them is with dental implants.  Implants Or False Teeth? Partial and full dentures have been a common solution for missing teeth for many years, but they have their disadvantages. They are prone to slipping and falling out if not properly secured, and they can lead to jaw pain and soreness in the gums. They also do not stimulate the jaw bones, so patients with dentures tend to suffer bone loss. Implants, on the other hand, are metal posts surgically placed in the jawbone under the gums and are basically a new root for a replacement tooth that looks and acts like a natural tooth. The only advantage dentures have over implants is that they are cheaper. It’s important to fill in the gap with an implant as soon as possible so the bone doesn’t erode and the surrounding teeth don’t collapse into the hole causing alignment and bite issues. Types Of Implants The health of the underlying jaw bone will determine a patient’s eligibility for implants and which type they will receive. In a patient with healthy bone, an endosteal implant will be used. This is simply a titanium post surgically placed into the jawbone. After a healing period, the patient will have a second surgery in which a crown is placed on top of the post. Visit us at: https://www.higginbothamfamilydental.com/dentist-little-rock-ar/
  • SPORTS INJURIES, ACCIDENTS, and tooth decay are just a few of the reasons we might lose a tooth. Thanks to modern dentistry, however, we don’t need to settle for having a gap in our smiles for the rest of our lives. There are a few ways to fill that gap, and one of them is with dental implants.  Implants Or False Teeth? Partial and full dentures have been a common solution for missing teeth for many years, but they have their disadvantages. They are prone to slipping and falling out if not properly secured, and they can lead to jaw pain and soreness in the gums. They also do not stimulate the jaw bones, so patients with dentures tend to suffer bone loss. Implants, on the other hand, are metal posts surgically placed in the jawbone under the gums and are basically a new root for a replacement tooth that looks and acts like a natural tooth. The only advantage dentures have over implants is that they are cheaper. It’s important to fill in the gap with an implant as soon as possible so the bone doesn’t erode and the surrounding teeth don’t collapse into the hole causing alignment and bite issues. Types Of Implants The health of the underlying jaw bone will determine a patient’s eligibility for implants and which type they will receive. In a patient with healthy bone, an endosteal implant will be used. This is simply a titanium post surgically placed into the jawbone. After a healing period, the patient will have a second surgery in which a crown is placed on top of the post. Visit us at: https://www.higginbothamfamilydental.com/dentist-little-rock-ar/
    Sep 26, 2018 60
  • 26 Sep 2018
    BECAUSE PREVENTION IS such a major part of good dental care, it’s critical to visit the dentist for regular checkups. We have our dental clinic in Memphis, TN for your complete family dental care. Residents nearby is offered for getting the best dental procedures in regular intervals of time. Higginbotham family dentist memphis, tn are dedicated in providing dental care for all signs of dental flaws. Family dentistry is what we care for as its easy for making schedule a single day appointment for dental treatments. This made easy for a family having littles, youngsters, couples, seniors to come along for the special family dental care in Memphis TN. We care for your smile throughout your lifetime and proud to offer best treatment in Memphis TN
  • BECAUSE PREVENTION IS such a major part of good dental care, it’s critical to visit the dentist for regular checkups. We have our dental clinic in Memphis, TN for your complete family dental care. Residents nearby is offered for getting the best dental procedures in regular intervals of time. Higginbotham family dentist memphis, tn are dedicated in providing dental care for all signs of dental flaws. Family dentistry is what we care for as its easy for making schedule a single day appointment for dental treatments. This made easy for a family having littles, youngsters, couples, seniors to come along for the special family dental care in Memphis TN. We care for your smile throughout your lifetime and proud to offer best treatment in Memphis TN
    Sep 26, 2018 58
  • 26 Sep 2018
    Manuka honey is not a commonly found honey, but it is a monofloral honey from the nectar of Manuka tree flowers and is produced only in New Zealand and some parts of Australia. The component present in Manuka honey has a high antibacterial property due to which it is popularly in demand. To identify the authenticity of Manuka honey, there is a standard grading system, UMF (Unique Manuka Factor) grading system. It actually shows the natural antibacterial strength of honey taken from Manuka tree. How to check the purity of Manuka Honey?   The higher the UMF Manuka Honey grade the greater the presence of the unique Manuka honey attributes. Low Grade:  UMF5 to UMF9Medium Grade:  UMF10 to UMF15Superior High Grade:  UMF16+ Manuka Honey USA is the only official US member of the UMF® Honey Association. Their goal is to provide customers with the excellent quality New Zealand Manuka honey and that too at affordable prices. If a bottle of Manuka honey is marked UMF 16+ that means this honey is of superior quality. They also offer Active Manuka Honey with Bee Venom. Active Manuka Honey is honey straight from the hive just as the bees made it. But, to extract it from the honeycomb, even raw Manuka Honey needs to be heated slightly to make it flow.  It also needs to be filtered slightly to remove the wax. The degree of heat and filtration are two of the many factors contributing to the differences in quality between the various brands of Active Manuka Honey.
    118 Posted by Manuka Honey USA LLC
  • Manuka honey is not a commonly found honey, but it is a monofloral honey from the nectar of Manuka tree flowers and is produced only in New Zealand and some parts of Australia. The component present in Manuka honey has a high antibacterial property due to which it is popularly in demand. To identify the authenticity of Manuka honey, there is a standard grading system, UMF (Unique Manuka Factor) grading system. It actually shows the natural antibacterial strength of honey taken from Manuka tree. How to check the purity of Manuka Honey?   The higher the UMF Manuka Honey grade the greater the presence of the unique Manuka honey attributes. Low Grade:  UMF5 to UMF9Medium Grade:  UMF10 to UMF15Superior High Grade:  UMF16+ Manuka Honey USA is the only official US member of the UMF® Honey Association. Their goal is to provide customers with the excellent quality New Zealand Manuka honey and that too at affordable prices. If a bottle of Manuka honey is marked UMF 16+ that means this honey is of superior quality. They also offer Active Manuka Honey with Bee Venom. Active Manuka Honey is honey straight from the hive just as the bees made it. But, to extract it from the honeycomb, even raw Manuka Honey needs to be heated slightly to make it flow.  It also needs to be filtered slightly to remove the wax. The degree of heat and filtration are two of the many factors contributing to the differences in quality between the various brands of Active Manuka Honey.
    Sep 26, 2018 118
  • 26 Sep 2018
    Higginbotham Family Dental is, once again, voted as the “best dental care provider” in Jonesboro. Our continued success is solely based on our hard work and the emphasis we place on the importance of advanced dental care to our clients. Our highly trained team is always ready to help and tend to your dental needs.   Let’s have peek into the system to better understand the success built around the dental care offered by Higginbotham Family Dental Clinics.   Customer Care   We have built a positive culture to never say no to our customers. If it is physically possible, we will do it. This is the positive attitude that has enabled HFD to attract a highly-trained team and grow into a network of dentists that help many of your friends and neighbors smile. Furthermore, we do not merely rest on our reputation. Our goal is to have everyone experience HFD, and we know this is one of the primary reasons why more than 80% of our new patients come from referrals. Excellent dental clinical care is the heart of Higginbotham Family Dental. Exceptional customer care is our soul.   Advanced Technology   At HFD, we are proud to support our team with advanced training, up-to-date materials and modern equipment. From oral cancer screening to conscious sedation and digital x-rays, HFD invests in the latest, proven technology. This commitment helps us take care of your smile while making each visit more comfortable and efficient. It is just part of what makes your experience at Higginbotham Family Dental great.   Emergency Care   As with many things in life, toothaches and cracked teeth often happen when least expected. Fortunately, most of our conveniently located dental offices are open Monday through Saturday. More importantly, our highly-trained dentists & staff make it possible for us to almost always see you the same day you call. While we hope you will never need this service, download our app today and keep our number handy… just in case an accident does happen.   All in One Clinic   Every requirement from emergency dental care to advanced cosmetic dentistry is addressed in our dental clinics. Our continued training process and adoption of advanced technology make us stand out among our competitors. We are at our best for the following services; SEDATION DENTISTRY, PRECISION DENTURES, BRACES,  DENTAL IMPLANTS, COSMETIC DENTISTRY, CLEANINGS & CHECKUPS and FAMILY DENTISTRY.     Dental Insurance Plans At HFD, we are proud to accept virtually every dental insurance plan. If you are fortunate to be among the 50% of the population who does have dental insurance, we want to help you put it to good use. If you are in the other half, we have great options for you as well. In fact, we have a dedicated team of highly-trained experts on-hand to help you understand your benefits and to answer all your questions – even before you become our patient.   Multiple Locations   We have spread out our wings amongst many locations to better serve our customers. All our clinics are equipped to address all possible dental care needs at affordable rates for our customers. Following are our established clinic locations : BLYTHEVILLE, AR; JONESBORO, AR – SOUTHWEST DR; WEST MEMPHIS, AR; BARTLETT, TN; PARAGOULD, AR; KENNETT, MO; JONESBORO, AR – HILLTOP; MEMPHIS, TN; ROGERS, AR.   Visit our web site to learn more information about our services and contact details or call us to schedule an appointment and discuss your dental needs.  www.higginbothamfamilydental.com
  • Higginbotham Family Dental is, once again, voted as the “best dental care provider” in Jonesboro. Our continued success is solely based on our hard work and the emphasis we place on the importance of advanced dental care to our clients. Our highly trained team is always ready to help and tend to your dental needs.   Let’s have peek into the system to better understand the success built around the dental care offered by Higginbotham Family Dental Clinics.   Customer Care   We have built a positive culture to never say no to our customers. If it is physically possible, we will do it. This is the positive attitude that has enabled HFD to attract a highly-trained team and grow into a network of dentists that help many of your friends and neighbors smile. Furthermore, we do not merely rest on our reputation. Our goal is to have everyone experience HFD, and we know this is one of the primary reasons why more than 80% of our new patients come from referrals. Excellent dental clinical care is the heart of Higginbotham Family Dental. Exceptional customer care is our soul.   Advanced Technology   At HFD, we are proud to support our team with advanced training, up-to-date materials and modern equipment. From oral cancer screening to conscious sedation and digital x-rays, HFD invests in the latest, proven technology. This commitment helps us take care of your smile while making each visit more comfortable and efficient. It is just part of what makes your experience at Higginbotham Family Dental great.   Emergency Care   As with many things in life, toothaches and cracked teeth often happen when least expected. Fortunately, most of our conveniently located dental offices are open Monday through Saturday. More importantly, our highly-trained dentists & staff make it possible for us to almost always see you the same day you call. While we hope you will never need this service, download our app today and keep our number handy… just in case an accident does happen.   All in One Clinic   Every requirement from emergency dental care to advanced cosmetic dentistry is addressed in our dental clinics. Our continued training process and adoption of advanced technology make us stand out among our competitors. We are at our best for the following services; SEDATION DENTISTRY, PRECISION DENTURES, BRACES,  DENTAL IMPLANTS, COSMETIC DENTISTRY, CLEANINGS & CHECKUPS and FAMILY DENTISTRY.     Dental Insurance Plans At HFD, we are proud to accept virtually every dental insurance plan. If you are fortunate to be among the 50% of the population who does have dental insurance, we want to help you put it to good use. If you are in the other half, we have great options for you as well. In fact, we have a dedicated team of highly-trained experts on-hand to help you understand your benefits and to answer all your questions – even before you become our patient.   Multiple Locations   We have spread out our wings amongst many locations to better serve our customers. All our clinics are equipped to address all possible dental care needs at affordable rates for our customers. Following are our established clinic locations : BLYTHEVILLE, AR; JONESBORO, AR – SOUTHWEST DR; WEST MEMPHIS, AR; BARTLETT, TN; PARAGOULD, AR; KENNETT, MO; JONESBORO, AR – HILLTOP; MEMPHIS, TN; ROGERS, AR.   Visit our web site to learn more information about our services and contact details or call us to schedule an appointment and discuss your dental needs.  www.higginbothamfamilydental.com
    Sep 26, 2018 66
  • 26 Sep 2018
    Hair is one particular of the vital sections of a human system. The hair lining safeguards the pores and skin towards outside the house damages of different layouts. Aside towards currently being an educational matter, they far too act as a design and style assertion. Maximum men and women comprise a fondness for fine and constructive hair. They create them appear elegant and enhance their self-esteem in the direction of an alternate place entirely. Regrettably, many persons won't be able to appreciate the privileges of Excellent hair owing toward their trouble of baldness. Baldness denies them the direction toward consist of favorable hair design. Nonetheless, with the development of science and technological know-how, there are services for this sort of issue. The optimum well-known and outstanding one particular is the hair transplantation technique. What is Hair Transplantation? This is a surgical procedure via which the difficulties of baldness, as nicely as strand reduction within Americans, can be settled towards a Wonderful extent. This method is a single of the highest popular kinds that are offered within the industry, and highest us citizens are likely towards like it thanks toward its successful and constructive expert services. The issue if baldness is a well-known position for highest humans. Hence, individuals who do not will need in the direction of being impacted through the point of baldness can consider out the most natural hair transplant treatment. The effective surgical or chemical strategies are constructed inside these a route that will repair men and women's scalp back again in the direction of its primary and natural and organic position. How does the method operate? The treatment of  chennai hair transplant includes the surgical transplantation of mane against distinctive components of the entire body in the direction of the greatest of the brain. The strategies do the job using making use of the fringe hair more than the aspects and back again of the scalp. This specific Room of strands is regarded as a result of the status of dominant donor hair. They consist of the energy towards acquiring upon a balding Place exactly where they are transplanted. 1 of the optimum well-liked and good transplantation treatments is the follicular device extraction or just recognized via the abbreviation of FUE. This is by way of much a single of the least complicated procedures of eliminating baldness, and this contains proved towards being a person of the ideal approaches as soon as when compared in the direction of the classic treatments. Within this sort of a method an extremely qualified as correctly as educated hair surgeon does the finish course of action towards assistance out their potential buyers towards not confront the condition of baldness and guidance within resolving any problems that occur in just the comprehensive technique. The perfect hair transplant strategy that is obtainable There are unique alternate options that are out there in the direction of us citizens who require in the direction of dwell a daily life that is composed of flaunting their elegant hair and displaying off their hair layout. One particular of the excellent procedures that are out there towards Americans is the Follicular gadget transplantation method. Way too recognized through its abbreviation, FUT, this procedure is from time to time regarded as a result of quite a few professionals within this marketplace, as the excellent a single that is offered by now. During this treatment, the healthcare provider donning out the do the job can go a good deal of hair strands inside of one appropriate consultation. There are unique positive aspects that are connected with this fashion of procedure. A person of the maximum visible positive aspects that are connected with this technique is the maximization of the mane transplant development. This method is a much far better one at the time as opposed in the direction of the standard procedures affiliated with the treatment. Another great usefulness linked with this technique is the strands of the particular person will appear to be organic and natural. The principal rationale of folks who will need in the direction of bringing out the method is they need to have their tresses toward appearing to be organic and desirable. All those can be involved with this procedure.  
    35 Posted by Play Hair
  • Hair is one particular of the vital sections of a human system. The hair lining safeguards the pores and skin towards outside the house damages of different layouts. Aside towards currently being an educational matter, they far too act as a design and style assertion. Maximum men and women comprise a fondness for fine and constructive hair. They create them appear elegant and enhance their self-esteem in the direction of an alternate place entirely. Regrettably, many persons won't be able to appreciate the privileges of Excellent hair owing toward their trouble of baldness. Baldness denies them the direction toward consist of favorable hair design. Nonetheless, with the development of science and technological know-how, there are services for this sort of issue. The optimum well-known and outstanding one particular is the hair transplantation technique. What is Hair Transplantation? This is a surgical procedure via which the difficulties of baldness, as nicely as strand reduction within Americans, can be settled towards a Wonderful extent. This method is a single of the highest popular kinds that are offered within the industry, and highest us citizens are likely towards like it thanks toward its successful and constructive expert services. The issue if baldness is a well-known position for highest humans. Hence, individuals who do not will need in the direction of being impacted through the point of baldness can consider out the most natural hair transplant treatment. The effective surgical or chemical strategies are constructed inside these a route that will repair men and women's scalp back again in the direction of its primary and natural and organic position. How does the method operate? The treatment of  chennai hair transplant includes the surgical transplantation of mane against distinctive components of the entire body in the direction of the greatest of the brain. The strategies do the job using making use of the fringe hair more than the aspects and back again of the scalp. This specific Room of strands is regarded as a result of the status of dominant donor hair. They consist of the energy towards acquiring upon a balding Place exactly where they are transplanted. 1 of the optimum well-liked and good transplantation treatments is the follicular device extraction or just recognized via the abbreviation of FUE. This is by way of much a single of the least complicated procedures of eliminating baldness, and this contains proved towards being a person of the ideal approaches as soon as when compared in the direction of the classic treatments. Within this sort of a method an extremely qualified as correctly as educated hair surgeon does the finish course of action towards assistance out their potential buyers towards not confront the condition of baldness and guidance within resolving any problems that occur in just the comprehensive technique. The perfect hair transplant strategy that is obtainable There are unique alternate options that are out there in the direction of us citizens who require in the direction of dwell a daily life that is composed of flaunting their elegant hair and displaying off their hair layout. One particular of the excellent procedures that are out there towards Americans is the Follicular gadget transplantation method. Way too recognized through its abbreviation, FUT, this procedure is from time to time regarded as a result of quite a few professionals within this marketplace, as the excellent a single that is offered by now. During this treatment, the healthcare provider donning out the do the job can go a good deal of hair strands inside of one appropriate consultation. There are unique positive aspects that are connected with this fashion of procedure. A person of the maximum visible positive aspects that are connected with this technique is the maximization of the mane transplant development. This method is a much far better one at the time as opposed in the direction of the standard procedures affiliated with the treatment. Another great usefulness linked with this technique is the strands of the particular person will appear to be organic and natural. The principal rationale of folks who will need in the direction of bringing out the method is they need to have their tresses toward appearing to be organic and desirable. All those can be involved with this procedure.  
    Sep 26, 2018 35
  • 26 Sep 2018
    Depression and lack of motivation can be serious problems for older people to deal with. And whilst it may not be possible to prevent feelings of frustration, worthlessness and anxiety there are many ways in which home care services can provide support and improve your outlook. Mr Motivator Your home help may not come dressed in lycra but they can still provide you with the motivation to get out and about. If confidence in your abilities is lacking, perhaps because you have fallen or are anxious, they can provide companionship and assistance so that you can continue to enjoy your garden and meet your friends. This, in turn, can have a positive effect on your mood and stave off depression. Familiarity Many older people find themselves getting confused in new situations. This can be especially acute if they are suffering from dementia. Moving into a care home, assisted living or your son’s spare bedroom can be a surprisingly difficult move to make. You will need to get used to a different layout of furniture and facilities,  a different routine and different people. Perhaps the biggest advantage of employing a live in care assistant is that you don’t need to make that move. You can continue to live in the same home, with the same décor and meet with the same friends as you did when you were more able to care for yourself. Companionship Having someone around has a soothing effect on most people. If you are living alone it can have a positive effect on your mental state to have someone there who you know is looking out for you. They will take on the burden of housework and cooking so you no longer need to worry about when you last dusted the ornaments or what you should eat for tea. And of course, perhaps most importantly, they will always be there to sit down with a cup of tea and have a chat. It is important to talk about how you feel. Bottling up emotions allows them to fester and strengthen. Your carer will always have time to sit down and listen to you. Specialist Dementia Care If you are in the early stages of dementia you may not require much in way of personal care – you may still be pretty fit and healthy physically. A live-in carer will be able to provide you with the precise level of support that you do require – whether that is reminding to take medication or ensuring that you do not have an accident when cooking. Moving to a care home can be a big shock to the system, even more so if you have dementia. In fact the trauma caused by leaving your familiar surroundings can be so great that it can cause a massive worsening of your condition. Employing a specialist dementia carer to live-in will avoid such a huge upheaval and can ensure your dementia does not suddenly worsen.
    1009 Posted by Simon Hopes
  • Depression and lack of motivation can be serious problems for older people to deal with. And whilst it may not be possible to prevent feelings of frustration, worthlessness and anxiety there are many ways in which home care services can provide support and improve your outlook. Mr Motivator Your home help may not come dressed in lycra but they can still provide you with the motivation to get out and about. If confidence in your abilities is lacking, perhaps because you have fallen or are anxious, they can provide companionship and assistance so that you can continue to enjoy your garden and meet your friends. This, in turn, can have a positive effect on your mood and stave off depression. Familiarity Many older people find themselves getting confused in new situations. This can be especially acute if they are suffering from dementia. Moving into a care home, assisted living or your son’s spare bedroom can be a surprisingly difficult move to make. You will need to get used to a different layout of furniture and facilities,  a different routine and different people. Perhaps the biggest advantage of employing a live in care assistant is that you don’t need to make that move. You can continue to live in the same home, with the same décor and meet with the same friends as you did when you were more able to care for yourself. Companionship Having someone around has a soothing effect on most people. If you are living alone it can have a positive effect on your mental state to have someone there who you know is looking out for you. They will take on the burden of housework and cooking so you no longer need to worry about when you last dusted the ornaments or what you should eat for tea. And of course, perhaps most importantly, they will always be there to sit down with a cup of tea and have a chat. It is important to talk about how you feel. Bottling up emotions allows them to fester and strengthen. Your carer will always have time to sit down and listen to you. Specialist Dementia Care If you are in the early stages of dementia you may not require much in way of personal care – you may still be pretty fit and healthy physically. A live-in carer will be able to provide you with the precise level of support that you do require – whether that is reminding to take medication or ensuring that you do not have an accident when cooking. Moving to a care home can be a big shock to the system, even more so if you have dementia. In fact the trauma caused by leaving your familiar surroundings can be so great that it can cause a massive worsening of your condition. Employing a specialist dementia carer to live-in will avoid such a huge upheaval and can ensure your dementia does not suddenly worsen.
    Sep 26, 2018 1009
  • 25 Sep 2018
    As any busy professional knows, squeezing in a little “me-time” is basically a myth. If it’s not juggling meetings, it’s finishing a project. Professionals tend to focus on directly what is in front of them rather than dealing with outside issues that might need a little more attention – like personal time. Easier said than done for most on-the-move pros. If it’s not on your calendar, it’s not on your schedule. Learning how to fit certain outside tasks into your daily operation may prove difficult, but it certainly isn’t impossible. This is especially true when those exterior items might help you with your overall professional lifestyle. So take a breather between those meetings and check out a few reasons why yoga might be the perfect outlet for even the busiest among us. Focus and Balance If focus isn’t t the top of your list as a busy professional then it’s guaranteed to at least make the top ten. Focus is what fuels you. You focus on every part of your work as well as balancing those things. Focus and balance are one in the same for a professional on the move. With focus, your mind is occupied trying to put the small pieces of a huge jigsaw puzzle together. With balance, you’re just trying to find the most efficient way to get that puzzle finished while also keeping another five puzzles going at the same time. Yoga can help you ensure your tent poles of balance and focus are where they need to be. Slow, steady meditation can clear your mind. Breathing exercises will give you the patience you need to balance everything on your place. Yoga can help you create harmony between balance and focus. Energy If you’re not big on exercise then this tip might seem a little counterintuitive. Yoga should make you more tired, right? Wrong! One of the most beautiful – and beneficial – parts of yoga is the fact that it actually increases your energy levels, and not just physically. The variety of different types of yoga lends itself well to different types of personalities and needs. You may need a yoga style that is centered around a lot of deep thinking time. Other yoga types of yoga can give you a workout that pushes your athletic buttons. But truthfully, all the different types of yoga have one thing in common. Their daily practice can give you more energy to burn throughout the day than you thought was possible. A steady routine of daily yoga to start your morning can do wonders for the rest of your day. Self-Care Busy professionals aren’t known to have a lot of “me-time” as mentioned in the introduction. Your “me” time often includes your commute to and from work, breaks here and there, and whatever time you manage to squeeze in at the end of the day. Consider taking on yoga to bridge the gap between a sliver of time for yourself and actual time you’ve carved out for self-care. Yoga can give you the presence to understand how vital self-care is to your overall daily life. Self-care is more than just popping a daily vitamin throughout the week. It’s about making sure you have time to nurture your mind as well as your body.   Interested in learning more about our yoga classes? We would love to see you at our studio, contact us at 703-887-9574 to book a slot. Also check us out our 4 for 40 new student special that’s available for a limited time.   https://www.piesfitnessyoga.com
  • As any busy professional knows, squeezing in a little “me-time” is basically a myth. If it’s not juggling meetings, it’s finishing a project. Professionals tend to focus on directly what is in front of them rather than dealing with outside issues that might need a little more attention – like personal time. Easier said than done for most on-the-move pros. If it’s not on your calendar, it’s not on your schedule. Learning how to fit certain outside tasks into your daily operation may prove difficult, but it certainly isn’t impossible. This is especially true when those exterior items might help you with your overall professional lifestyle. So take a breather between those meetings and check out a few reasons why yoga might be the perfect outlet for even the busiest among us. Focus and Balance If focus isn’t t the top of your list as a busy professional then it’s guaranteed to at least make the top ten. Focus is what fuels you. You focus on every part of your work as well as balancing those things. Focus and balance are one in the same for a professional on the move. With focus, your mind is occupied trying to put the small pieces of a huge jigsaw puzzle together. With balance, you’re just trying to find the most efficient way to get that puzzle finished while also keeping another five puzzles going at the same time. Yoga can help you ensure your tent poles of balance and focus are where they need to be. Slow, steady meditation can clear your mind. Breathing exercises will give you the patience you need to balance everything on your place. Yoga can help you create harmony between balance and focus. Energy If you’re not big on exercise then this tip might seem a little counterintuitive. Yoga should make you more tired, right? Wrong! One of the most beautiful – and beneficial – parts of yoga is the fact that it actually increases your energy levels, and not just physically. The variety of different types of yoga lends itself well to different types of personalities and needs. You may need a yoga style that is centered around a lot of deep thinking time. Other yoga types of yoga can give you a workout that pushes your athletic buttons. But truthfully, all the different types of yoga have one thing in common. Their daily practice can give you more energy to burn throughout the day than you thought was possible. A steady routine of daily yoga to start your morning can do wonders for the rest of your day. Self-Care Busy professionals aren’t known to have a lot of “me-time” as mentioned in the introduction. Your “me” time often includes your commute to and from work, breaks here and there, and whatever time you manage to squeeze in at the end of the day. Consider taking on yoga to bridge the gap between a sliver of time for yourself and actual time you’ve carved out for self-care. Yoga can give you the presence to understand how vital self-care is to your overall daily life. Self-care is more than just popping a daily vitamin throughout the week. It’s about making sure you have time to nurture your mind as well as your body.   Interested in learning more about our yoga classes? We would love to see you at our studio, contact us at 703-887-9574 to book a slot. Also check us out our 4 for 40 new student special that’s available for a limited time.   https://www.piesfitnessyoga.com
    Sep 25, 2018 49
  • 25 Sep 2018
    Nerve Renew This is a appealing array for double entendre the art doesn't move down the folic devil-may-care cases. The bells personal property: Pricing, declining on and cheese-paring Nerve Renew offers seven compartments for $239, five holders for $197 and four compartments for $124. We didn't hooker pleb beseech of auto-dispatching, a waylay habituated to by alternative totalling happening to thusly attribute you for all the all the all the extension function on gonfalon breaks as special to by the aggregate you pelt on your first sue. Penurious substructure be obligated main Nerve Renew 30 generation of your business date. To defend an area, you phone call to call Nerve Renew's buyer leaning selection to acquire a compass quantity (RMA). The RMA attack be seconded median or outside of the booth you recital to give back your supplements. The modus operandi of action's buyer be cautious hum quantity is 800-409-3994. Our decisions about paying compressed regard to whether Nerve Renew substructure second you Nerve Renew baffled us after studies feel sorry a position the unite flag vitamins in the pills go certainly faultless up being useful to patients.   https://pocket2coins.com/nerve-renew/
    42 Posted by vaide kevy
  • Nerve Renew This is a appealing array for double entendre the art doesn't move down the folic devil-may-care cases. The bells personal property: Pricing, declining on and cheese-paring Nerve Renew offers seven compartments for $239, five holders for $197 and four compartments for $124. We didn't hooker pleb beseech of auto-dispatching, a waylay habituated to by alternative totalling happening to thusly attribute you for all the all the all the extension function on gonfalon breaks as special to by the aggregate you pelt on your first sue. Penurious substructure be obligated main Nerve Renew 30 generation of your business date. To defend an area, you phone call to call Nerve Renew's buyer leaning selection to acquire a compass quantity (RMA). The RMA attack be seconded median or outside of the booth you recital to give back your supplements. The modus operandi of action's buyer be cautious hum quantity is 800-409-3994. Our decisions about paying compressed regard to whether Nerve Renew substructure second you Nerve Renew baffled us after studies feel sorry a position the unite flag vitamins in the pills go certainly faultless up being useful to patients.   https://pocket2coins.com/nerve-renew/
    Sep 25, 2018 42
  • 25 Sep 2018
    Original article: https://www.perfectketo.com/what-is-betahydroxybutyrate-or-bhb/   If you had to choose between: An inefficient fuel that  leaves a trail of smoke and slowly damages your car A clean fuel that gives you more mileage and keeps your car running smoothly It’s a no-brainer to pick option B, right? Well, you have to make that same decision when it comes to the fuel your body runs on, and guess what? Most people pick option A every day. The human body can choose between two different fuels: glucose (from carbs) and ketone bodies (from fat).   One ketone body called BHB is the clean and effective fuel your body can use for energy, yet you probably didn’t hear about it at school… or anywhere, really. That’s about to change. This article will break down everything you never knew you needed to know about BHB (and why it’s the fuel your body has been missing out on): What Is Beta-Hydroxybutyrate (BHB)? When BHB Is Necessary Types of BHB How Your Body Makes and Uses BHB BHB vs. Glucose 10 Reasons Beta-Hydroxybutyrate (BHB) Is a Rockstar Fuel How to Optimize BHB Levels What Are BHB Salts or Exogenous BHB? How Exogenous BHB Salts Are Made 5 Benefits of Taking Exogenous BHB Killer Combo: BHB Salts + MCTs Can I Take BHB Salts While Fasting? How to Choose The Best BHB Salts How to Take BHB Salts How to Check Your BHB Levels Are BHB Salts Safe? WHAT IS BETA-HYDROXYBUTYRATE (BHB)? Beta-hydroxybutyrate (BHB), is one of the three ketone bodies (energy molecules) your body makes when it’s running on fat instead of carbs. It’s also known as 3-hydroxybutyric acid or 3-hydroxybutanoic acid (3HB)[*]. The three main ketones your body makes from fatty acids are: Beta-hydroxybutyrate (BHB). This is the most abundant, making up to 78% of total ketones in the blood[*]. Acetoacetate (AcAc). It makes up around 20% of ketones in the blood. Acetone. The least abundant, making about 2% of ketones in the blood. It’s not used for energy. Both BHB and acetone are derived from acetoacetate (AcAc), however, BHB is the main ketone used for energy because it’s extremely stable and abundant, while acetone is lost through respiration and sweat. Your body makes two types of BHB[*][*]: D-BHB: This is the one your cells use for efficient energy and its produced in high amounts. It’s responsible for the anti-aging effects of total BHB. L-BHB: This one is produced in lower quantities and can’t be used for energy as efficiently as D-BHB. It’s more helpful in the synthesis of fatty acids. Ketosis is the metabolic state of using ketones — both BHB and AcAc — for energy instead of glucose. If you’re wondering — why would I need to switch fuels? The answer is simple: BHB works better. It’s not unnatural or harmful — in fact, it’s the opposite. 10 REASONS BETA-HYDROXYBUTYRATE (BHB) IS A ROCKSTAR FUEL BHB has more advantages beyond efficient energy production. It can supercharge your metabolism in ways glucose can’t. Here are just 10 reasons to make the switch: #1: ENHANCES GENE EXPRESSION A lot of the benefits of BHB come from its ability to optimize the expression of your genes, aka the way your cells interpret DNA instructions. That’s why we’re starting with it. Quick DNA function refresh: DNA is the biological code that specifies how organisms grow, function, and reproduce, which rarely changes. DNA expression is simply how well this code is passed down to your cells, which can vary depending on several factors.   You can think of DNA as the assembly instructions for building an IKEA chair, and DNA expression how well you interpret them to actually build the chair. If DNA expression is impaired (you can’t understand the instructions), your cells can’t create the proteins they need to survive. DNA expression involves two steps: Transcription: The DNA instructions for making a specific protein are copied into a messenger molecule called mRNA (think of printing your chair instructions). Translation: The mRNA is read and used to assemble the correct amino acids that form the protein (think of reading the instructions to assemble your chair). BHB improves gene expression by inhibiting molecules that silence important proteins[*].  It makes helpful genes available for expression, including FOXO and MTL1. The FOXO genes regulate oxidative stress resistance, metabolism, cell cycle, and apoptosis, which influences longevity and lifespan. MLT1 can help reduce toxicity[*]. Takeaway: BHB improves gene expression by unlocking important proteins that increase longevity and antioxidant protection. #2: SUPERCHARGES COGNITIVE FUNCTION Ketones are able to cross the blood-brain barrier easily and provide your brain with over 70% of its energetic needs[*]. This is possible because your brain becomes extremely receptive to ketone bodies when there’s not enough glucose around. In fact, neurons consume a lot of BHB, at a rate of 0.032 mmol/kg/min[*]. This quick absorption improves brain function in many ways, including: Preservation of neurons and synapses — which improves memory, focus, attention, and learning. Fewer free radicals Lower neuroinflammation Lower risk of dementia Reduced risk of depression and mood disorders Improved cognition in people with dementia, including those with  Alzheimer’s and Parkinson’s disease[*]. In one study, an increase of BHB in the brain 90 minutes after ingesting MCT oil improved paragraph recall in adults with impaired memory[*]. Preliminary studies also show ketones can improve working memory in both young and old subjects[*][*]. Another study found BHB has antidepressant and antianxiety-like effects because it prevents neuroinflammation in the hippocampus[*]. Multiple studies suggest BHB may be beneficial in preventing neurodegenerative diseases, including Huntington’s disease, Parkinson’s disease, and Alzheimer’s disease by improving mitochondrial respiration, preventing the accumulation of a toxic molecule called amyloid-β, and preventing brain atrophy[*]. BHB also protects the central nervous system by preserving an important type of cell present in the brain and spinal cord called ramified microglia, which acts as a sensor scanning for potential threats and protects neurons[*][*]. Takeaway: Your brain can absorb ketones quickly, and ketones protect neurons, synapses, lower neuroinflammation, and prevent neurodegeneration.    #3: KILLS INFLAMMATION BHB blocks a platform responsible for inflammation called NLRP3 inflammasome[*][*]. NLRP3 unleashes inflammatory molecules that trigger neuroinflammation, cancer, insulin resistance, bone diseases, Alzheimer’s disease, skin diseases, metabolic syndrome, type 2 diabetes, and gout[*]. Research shows BHB can destroy these inflammatory molecules: In one study, BHB administration decreased the inflammatory molecules IL-1β  and TNF-α in the hippocampus[*]. Another study showed BHB reduced the inflammatories interleukin IL-1β and IL-18 in human white blood cells[*]. This anti-inflammatory power makes BHB useful for preventing diseases triggered or aggravated by inflammation. For example, it may help treat inflammatory skin diseases like acne, psoriasis, varicose ulcers, allergic reactions, and skin photosensitivity[*]. Takeaway: BHB blocks the activity of the complex NLRP3 inflammasome, which is responsible for major inflammation in the body. #4: FIGHTS OXIDATIVE STRESS Remember that turning BHB into energy improves antioxidant protection by increasing the NAD+/NADH ratio and unlocking antioxidant genes? These protective effects are far-reaching. Evidence finds BHB can prevent and reverse oxidative damage in the brain (neurons, hippocampus, neocortex) and blood: One study found BHB prevented neuronal death. [*] In the hippocampus, — the part of your brain that regulates emotions, long-term memory, and spatial navigation — BHB protects the integrity of neuron synapses against oxidative damage. [*] In the neocortex, — the brain area responsible for higher-order functions like cognition, spatial reasoning, language, and sensory perception —  BHB protects neurons from oxidation. [*] In endothelial cells (cells lining the inside of your blood vessels), ketones activate antioxidant defenses, which protects the cardiovascular system. [*] Another study done on athletes found ketone bodies reduced the oxidative stress caused by exercise. [*] Takeaway: The antioxidant effects of manufacturing BHB protect your cells against oxidative damage, especially in the brain. > #5. INCREASES LIFESPAN BHB can help you live a longer, healthier life thanks to: Its positive effects on gene expression Its anti-inflammation powers (as explained before). Basically, BHB unlocks helpful genes that work together to fight oxidative stress and improve metabolism, increasing longevity. [*] This is how BHB taps into your anti-aging genes: Blocks the insulin-like growth factor (IGF-1) receptor gene. This gene’s role is boosting cell growth and proliferation, but excessive growth is linked to diseases and early death. A lower activity of IGF-1 delays aging and increases lifespan.[*] Activates FOXO genes. One gene in particular, FOXO3a, is linked to increased longevity in humans because it boosts antioxidant creation.[*] Since BHB also suppresses inflammation, it prevents age-related inflammatory diseases that cause functional decline and early death, including arthritis and bone loss. [*] Takeaway: BHB can increase lifespan by activating anti-aging genes and slashing inflammation. #6. HELPS FIGHT AND PREVENT CANCER BHB can slow down the growth of tumors because cancer cells can’t use ketones well enough to grow and spread. This phenomenon is explained by Warburg’s effect, which says cancer cells and tumors depend on glucose breakdown (glycolysis) to grow, in contrast to healthy cells that can use either glucose or ketones.[*] Scientists exploited this weakness by taking away glucose and forcing cancer cells to depend on ketones, and it actually decreased tumors in many organs including the brain, pancreas, and colon, because the cells were unable to spread. Here’s what different studies have found: Ketones slowed down brain tumor growth by lowering blood glucose and IGF-1 (two factors that encourage tumor progression).[*] In other words, when ketones replaced glucose as fuel, brain tumors shrank. Ketones stopped the spread of metastatic cancer cells both in vivo and in vitro.[*] Ketone bodies killed pancreatic cancer cells and diminished cachexia. Cachexia is a syndrome that up to 80% of people with advanced cancer have, and consists of extreme weight loss, fatigue, and muscle atrophy.[*] Ketones also slowed down the growth neuroblastomas, cancer cells that form in nerve tissue.[*] Takeaway: Running on BHB impairs the growth of tumors. #7. BOOSTS INSULIN SENSITIVITY Ketones improve insulin sensitivity by reducing insulin levels as well as blood glucose and mimicking the effects of insulin.[*][*] This can reverse insulin resistance — what happens when your body is forced to make extra insulin to deal with blood sugar. When you’re sensitive to insulin, you’re at a lower risk of metabolic diseases such as type 2 diabetes, non-alcoholic fatty liver disease, and obesity. Takeaway: BHB can improve insulin sensitivity and reverse insulin resistance by keeping glucose and insulin levels low. #8. OPTIMIZES HEART FUNCTION Did you know that your heart’s preferred energy source are long-chain fatty acids? In the normal adult heart, fatty acids provide up to 70% of the ATP,  while glucose, lactate, amino acids, and ketones supply the rest.[*] Note: Using fats and using ketones are not the same thing. The heart metabolizes fat directly, without turning it into BHB first. However, just like the brain, your heart can adapt extremely well to ketones if needed. It automatically learns to regulate the breakdown of ketones, thanks to the remarkable metabolic flexibility of heart cells. Burning BHB is more energetically efficient for the heart than using fatty acids because: BHB improves its mechanical efficiency and blood flow. Burning fatty acids increases free radicals, while BHB destroys them. Studies found the mechanical efficiency of the heart increased by 30% and blood flow increased by 75% when running on ketones.[*][*][*] Takeaway: BHB is a better fuel for the heart. It protects against oxidative damage, enhances mechanical efficiency, and improves blood flow. #9: BOOSTS FAT LOSS AND WORKOUT PERFORMANCE Your skeletal muscle also benefits from BHB, especially when exercising. Exercise increases the absorption of ketones dramatically, and in turn ketones improve performance and recovery. It’s a cycle of goodness. In short, ketones can: Improve performance during endurance exercises (cycling, hiking, dancing, swimming, power yoga, playing sports, or walking long distances) Increase fat loss without reducing muscle mass in resistance exercises Increase fat burning Replenish glycogen stores and accelerate recovery Endurance exercises in particular accelerate the absorption of BHB. One study found the rate of ketone consumption increased three to five fold during 30 min of cycling exercise. Ketones ended up providing 85–125 kJ of energy over 30 min of exercise, compared to just 27 kJ during 30 min of rest.[*] This increased absorption triggers more fat burning. One study found the burning of intramuscular fat jumped 20-fold during exercise on ketosis, even when there was muscle glycogen available. This means the cells ignored the usually-preferred glucose reserves and burned more fat instead.[*][*] This leads to accelerated fat loss. People who do resistance training on ketosis lose fat mass quicker, without losing lean muscle.[*][*] Thanks to this focus on fat, the body is able to replenish glycogen quicker after a workout, which seriously improves recovery. One study found that when BHB levels increased, both glycogen and glucose uptake rate also increased after a workout. This is a big deal because your muscles can only use glycogen for recovery.[*] Lastly, ketones can decrease fatigue and improve cognitive function when exercising.[*] Takeaway: Exercises accelerates the absorption of BHB, and BHB boosts fat burning, recovery, and energy. #10: PREVENTS BONE DETERIORATION BHB has impressive bone preserving abilities. Research finds it can prevent bone degradation by stopping the production of cells called osteoclasts in subjects with osteoporosis.[*][*] You’ve probably heard of osteoblasts, which are cells that produce the matrix for bone formation.They create bones. Osteoclasts are the exact opposite. Their name comes from the words “osteon” (bone) and “clastos” (broken). Their job is to break down bone tissue, which is helpful in bones of healthy people, but terrible in people with osteoporosis and other bone diseases.   By stopping osteoclasts, BHB reverses and possibly prevents bone break down. It can also strengthen your bones. One study[*] found BHB: Prevented bone density decline Increased resistance to bone deformation Boosted the strength of the femur Improved the volume of the internal tissue of the bone (called cancellous or spongy bone) Takeaway: BHB prevents the growth of cells that break down bone tissue and increases bone strength and resistance. Now that you’re up to speed with the perks of running on BHB, here’s how to make sure you’re making enough of it: HOW TO OPTIMIZE BHB LEVELS Swapping glucose for BHB is extremely beneficial, but our food environment makes it a challenge. These 4 things will help you maintain consistent levels of ketones: #1: FOLLOW A KETOGENIC DIET Starting a ketogenic diet is the first thing you should do if you’re serious about running on ketones. Mistakenly, the ketogenic diet is often lumped with other low carb diets, but keto is the only diet that changes your metabolism from burning sugar to burning fat. Its recommended macros of 70-80% fat, 20-25% protein, and 5-10% carbs are designed to make your body produce more BHB and AcAc so you can enter and remain in nutritional ketosis. You can expect your blood ketones to stay between 0.6 and 3.0 mmol/L. Here’s the gist of what you can eat on the ketogenic diet: Healthy fats: Avocado, coconut oil, MCT oil, avocado oil, walnut oil, olive oil. Dairy: cream cheese, cheeses, sour cream, butter, ghee. Cage-free eggs. Red meats: grass-fed beef, organs, game meat, lamb, bison, pork. White meats: pastured chicken, turkey, duck. Fish and seafood: Especially fatty fish like mackerel, sardines, and salmon. Nuts and seeds: Nut butter, macadamia nuts, cashews,  walnuts, almonds, chia seeds, flaxseed. Low-starch veggies: Spinach, kale, lettuce, collard greens, zucchini, tomato. Low glycemic fruits (in small quantities if at all): blueberries, strawberries, cherries. Keto-friendly snacks: Low-carb cookies, flourless pancakes, keto frappuccino. Yes, being on keto means you’ll have to brush up on your cooking skills a little bit, but it’s not hard to cook keto meals (few ingredients!) and you’ll feel amazing afterward. For more info on what to eat, what to avoid, and what recipes to make, read these: The Ultimate Start Up Guide to The Ketogenic Diet Full Ketogenic Diet Food List Keto Fruit: The Essential Guide to Nature’s Candy on a Low Carb Diet Ketogenic Diet Foods to Avoid: 108 Foods That’ll Slow Your Fat Loss Keto Recipes for Breakfast, Lunch, Dinner, and Dessert Find out your personal macros with the Keto Calculator. #2. DO INTERMITTENT FASTING Doing intermittent fasting will help you enter or get back into BHB-burning mode quickly. Unlike regular fasting (not eating for several days), intermittent fasting is done for just a portion of the day, and it gives you the same cognitive and longevity benefits. There are several ways to do intermittent fasting, but the most common is to eat in a limited window of time during the day and fast the remaining hours. Usually, people fast for 16 hours a day and eat in an 8-hour window. For example, you could fast from 08:00 pm to 12:00 pm, and eat from 12:00 pm to 08:00 pm. Fasting this way will: Increase your BHB levels above 0.6 mmol/L Activate autophagy (the cleaning up of old cells) Support healthy weight loss If you combine a ketogenic diet with intermittent fasting, you’ll be able to run on ketones more easily. #3. AVOID HIDDEN CARBS Our food environment works hard to make us rely on sugar for energy. Carbs are hidden everywhere, in “healthy” snacks, beverages, and restaurant meals. If you’re not careful, you can surpass the small number of daily carbs you can eat on ketosis, which is around 30g. Want to know how easy it is to hit or pass your daily carb limit? A medium banana has 27g of carbs. A Nature Valley Oats ‘n Honey Crunchy Granola bar has 31g of carbs. A medium baked potato has 37g of carbs. One small buttered popcorn has 37g of carbs. A grande mocha Frappuccino with regular milk has 61g carbs.[*] If you eat too many carbs, your body will switch back to burning glucose, not BHB, and you will miss out on all the metabolic and cognitive benefits of ketones. Bummer. You can avoid eating excess carbs by: Sticking to real food. Avoid packaged snacks and drinks as often as possible. Always reading labels at the supermarket. Cooking at home more often. Googling what doesn’t have labels. If possible, check the nutrition facts for the places you frequent. Here are the nutritional facts of the menu from Starbucks, Red Lobster, Applebee’s, Outback Steakhouse, TGI Friday’s,Chipotle, Subway, and In-n-Out. Check more restaurants with MyFitnessPal. Avoiding fast food restaurants altogether. #4. TAKE BHB SALTS Of course, you could save yourself a lot of work and boost your BHB levels effortlessly by taking exogenous ketonesin the form of BHB salts. They will: Raise your BHB levels wickedly fast. Save you the 12+ hours it takes your body to increase BHB levels from scratch. Help you avoid the keto flu if you’re a beginner. BHB salts are completely safe and a total game changer if you want to reap the full benefits of ketosis. When you combine a ketogenic diet, intermittent fasting, and BHB salts, running on BHB is extremely easy. WHEN BHB IS NECESSARY The human body can efficiently burn BHB for energy because… We’ve been doing it for hundreds of thousands of years. It’s how our ancestors survived. Our bodies are literally born to do so. Let’s back up a bit: Humans in the hunter-gatherer era survived thanks to metabolic flexibility — the body’s ability to use different fuels for energy depending on the nutrients available. This adaptation was vital during a time when the source, quantity, and frequency of food was uncertain[*]. Most of the time, people were fasting, so their bodies ran on ketones, not glucose. Nowadays, most adults rely on glucose for energy thanks to the abundance of high carb foods, but we’re all born needing and using ketones. Children can produce and use BHB more efficiently than adults because, in the early days of life, ketones (BHB and AcAc) are better than glucose for brain growth and lung function. At this stage, blood ketones can reach 2–3 mmol/L (micromolar per liter), the same levels as in a ketogenic diet[*]. This ability is to burn ketones is never lost. Elderly people are able to generate ketones after a fast or a ketogenic meal at the same levels as younger adults. If we wanted, we could keep using ketones for energy throughout our adult life like we did as infants. Sadly, our food environment pushes us to ditch ketones and rely on glucose when we grow up. Unless you’re a baby, a regular keto-er, a carnivore, diabetic, or a caveman, your body runs on glucose. The good news is, it’s easy to start using ketones for fuel again. Your body is always making BHB and AcAc, but on a regular carb-based diet, the levels remain below 0.5 mmol/L (micromolar per liter), which isn’t enough to fuel your cells. Only certain conditions[*][*] can boost BHB levels high enough to make the fuel switch: Following a ketogenic diet. On low carb, high fat ketogenic diet, your body will produce consistent ketone levels above 2 mmol/L. Fasting. BHB levels rise above 0.6 mmol/L after 12–16 hours of fasting and reach 1–2 mmol/L after 2 days of fasting. Doing Intense Exercise. Doing intense exercise for 90 minutes can boost BHB to 1–2 mmol/L. In these three circumstances, your body doesn’t have access to enough carbs (glucose) or stored glucose (glycogen), so it turns to stored fat for energy. The fatty acids are metabolized by your liver into ketones (mostly BHB), which can be used by your cells as an efficient fuel source. When your ketone levels are consistently between 0.6 and <3 mmol/L, you’re in nutritional ketosis, which has many advantages, including: Increased cognitive function (clearer thinking, higher focus) Stable blood sugar More energy Healthy weight loss Accelerated fat loss Better workout performance During therapeutic treatments under the supervision of a physician, your blood BHB may rise up to 10 mmol/L. There are other circumstances that push your body to make more ketones, but these are detrimental to your health and should not be attempted: Not monitoring insulin levels as a diabetic. If insulin levels are not controlled in diabetic patients, they can drop dramatically and make your body overproduce ketone bodies above 3 mmol/L. This may provokeketoacidosis, which can be lethal (more on that later). Entering starvation mode after extended fasts. Prolonged starvation will increase ketones to  6–8 mmol/L, but it’s not the healthiest approach. What’s the point of making lots of efficient BHB if you’re going to starve yourself and miss out on important nutrients? Remember, being in ketosis doesn’t mean you’re healthy. The best way to reap all the health benefits of BHB is to keep it in the range of nutritional ketosis. The three types of cells that consume the most BHB are: Cardiomyocytes (cardiac muscle cells). The heart is the highest ketone body consumer per unit mass[*]. Skeletal myocytes (skeletal muscle cells). Neurons. Normally, your brain and muscles rely heavily on glucose, while your heart burns long-chain fatty acids, but switching to BHB can enhance their function and provide extra protection against disease. THE TWO TYPES OF BHB Your body can use two forms of BHB: endogenous and exogenous. Endogenous BHB is the one your body makes by itself. “Endo” comes from the Greek éndon, which means “within”. Exogenous ketones are external BHB molecules you can take as a supplement to kickstart ketosis quickly, usually in the form of BHB salts or esters. “Exo” is the opposite of “endo” and means “external”. This article will discuss both of them. Let’s start by looking at how your body manufactures endogenous BHB from scratch: HOW YOUR BODY MAKES AND USES BHB The cycle of turning fats into BHB, and then BHB into energy, involves two processes: Ketogenesis: The production of BHB in the liver. It means ketone (keto-) generation (-genesis). Ketolysis: The process of transforming BHB into ATP (the energy currency of the cell). It means ketone (keto-) breakdown (-lysis). Both mechanisms involve complex chemical processes which are condensed below[*][*][*][*][*][*]: STEP #0: MAKING FREE FATTY ACIDS (LIPOLYSIS) Before BHB production begins, stored fat needs to be converted into free fatty acids.   Lipolysis is the process of turning triglycerides — stored in fat tissue — into glycerol and free fatty acids (FFA) that enter the blood and travel to the liver to be turned into BHB. PROCESS #1: KETOGENESIS Where: The mitochondria of liver cells Result: BHB BHB production happens in the mitochondria of liver cells (what is commonly known as the powerhouse of the cell), and it follows these steps: #1. Fatty acid activation (acyl-CoA): Before they’re able to cross the mitochondrial barrier, long-chain fatty acids need to be “activated” because the mitochondria only accepts short-chain fats. A molecule called Coenzyme A (CoA) is attached at the end of the fatty acid, and this combo is called acyl-CoA. #2. Fatty acid oxidation (acetyl-CoA): Once inside the mitochondria, acyl-CoA is broken down into acetyl-CoA.This a crucial molecule because it’s the only one that can enter the Krebs Cycle: #3. Krebs Cycle: Also known as the citric acid cycle (CAC) or tricarboxylic acid (TCA) cycle. This is the process that generates ketones and precursors of amino acids by breaking down acetyl-CoA. It works by fully oxidizing all molecules to carbon dioxide (CO2). The process for making BHB goes like this: Acetyl-CoA Acetoacetyl-CoA: acetyl-CoA degrades into acetoacetyl-CoA. HMG-CoA: Acetoacetyl-CoA degrades into HMG-CoA. Acetoacetate (AcAc): HMG-CoA turns into the first ketone, AcAc. BHB: AcAc is reduced to BHB, and acetone is produced as a by-product. PROCESS #2: KETOLYSIS Where: The mitochondria in cells of other organs except the liver Result: ATP Once BHB is released (ketogenesis), your heart, brain, and other organs absorb it to turn it into ATP — the energy currency. It will go through the Krebs cycle again, just a little differently: #1. Absorption by organs: When BHB is in the bloodstream, your organs — except your liver — take it up for energy. Ironically, the liver doesn’t have the ability to utilize ketones even though it makes them[*].   #2. Turning BHB back to acetyl-CoA: BHB has to turn back into acetyl-CoA because it’s the only molecule that can go through the Krebs cycle, remember? So, when BHB enters other organs, it retraces the steps it first took in the liver: BHB Acetoacetate (AcAc): BHB turns back into the first ketone. Acetoacetyl-CoA: Acetoacetate (AcAc) is turned back to this molecule. Acetyl-CoA: Acetoacetyl-CoA turns back to acetyl-CoA, which can enter the Krebs cycle. #3. Krebs Cycle: Acetyl-CoA completely oxidizes in the cycle, and this oxidation releases electrons into two carrier molecule: NADH or FADH2. #4. Oxidative phosphorylation (aka ATP creation): The electrons from NADH or FADH2 are transferred towards O2, which creates ATP. This is also called the mitochondrial respiratory chain. As you can see, using BHB for energy is an intricate process. Basically, acetyl-CoA can turn into BHB (in the liver), and then BHB has to turn back into acetyl-CoA to make usable energy (ATP in organs). In summary, BHB is created in the liver by oxidizing fats (ketogenesis). Then BHB is turned into ATP (energy) through oxidation in organs (ketolysis). Running on BHB gives you a metabolic advantage over glucose.   BHB VS. GLUCOSE AS FUEL If you’re curious to know exactly how BHB compares to glucose in terms of energy, here’s a breakdown of their: Energy Efficiency Energy Yield ENERGY EFFICIENCY Creating energy generates harmful by-products called free radicals, or oxidants. These molecules can damage cells and DNA, and they’re inevitable. During the production of ATP, the oxidants O2∙− and H2O2 are leaked. These are “tamer” free radicals that can be easily countered with antioxidants. However, under the wrong circumstances, they have the potential to run wild and turn into the most damaging free radicals: reactive nitrogen species (RNS) and hydroxyl radical (∙OH), which are responsible for most oxidative damage.[*] Therefore, it’s necessary to minimize free radicals during energy production and optimize antioxidants. The fuel your body uses and the resources they consume to create ATP influences how many free radicals are created and suppressed. The fewer free radicals a fuel creates, the more efficient it is. Glucose Efficiency Glucose goes through a slightly longer process than BHB before entering the Krebs cycle. Through glycolysis, glucose turns into pyruvate, and then pyruvate is turned into acetyl-CoA, which can enter the Krebs cycle. This path from glucose > pyruvate > acetyl-CoA eats up significant resources. One glucose molecule consumes 4 NAD+ molecules, which turn into 4 NADH. The ratio of NAD+/NADH matters because it regulates oxidant and antioxidant activity: NAD+ is the “good” molecule. It protects against oxidative stress, especially the oxidant H2O2, and improves autophagy (cleaning up damage cells). NAD+ is consumed as fuel for chemical reactions (like ATP production) and turns into NADH.[*] NADH is also necessary, mainly to produce ATP, but it doesn’t protect against damage. When there’s more NADH than NAD+, more free radicals are produced and helpful enzymes are inhibited.[*] In other words, the ratio of NAD+/ NADH should stay high. Low NAD+ causes serious oxidative damage. Because glucose consumes 4 NAD+ molecules from the get-go, it tips the scale towards more NADH, which can cause more oxidative damage.   BHB Efficiency BHB skips glycolysis. It only has to convert back to AcAc and then to acetyl-CoA before entering the Krebs cycle, a process that uses up half the resources as glucose. One BHB molecule consumes only 2 NAD+ molecules, which turn into 2 NADH. This means BHB is more efficient than glucose and protects the NAD+/NADH ratio. In fact, research[*] shows BHB not only preserves but increases the NAD+/NADH ratio, which can: Protect against oxidative stress and oxidants created during energy production Support mitochondrial function and biogenesis Provide anti-aging and longevity effects Increase the amount of free NAD+ than can be used for optimal gene expression BHB also reduces free radicals through protective proteins that only activate when your body runs on ketones: UCP: Fats accelerate the activity of the UCP protein. UCP kills the free radicals that leak during the creation of energy, preventing oxidative damage in the mitochondria.[*][*] SIRT3: When your body switches from glucose to fats, a protein called Sirtuin 3 (SIRT3) increases. It activates a powerful antioxidant called of MnSOD and other mitochondrial antioxidant systems to keep oxidants low during energy creation. It also stabilizes the FOXO genes, which protect against oxidation.[*] VERDICT Using BHB for fuel is more efficient than using glucose because it consumes less NAD+ molecules, increasing the NAD+/NADH ratio, which prevents oxidative damage and promotes longevity. It also fights the damage of inevitable free radicals by activating powerful antioxidants, which glucose doesn’t do. Energy Yield The energy yield is measured by two things: Number of ATP molecules created per molecule of BHB or glucose Usable energy from each ATP molecule Each molecule of glucose and BHB creates different amounts of ATP, which carries usable energy to your cells. When ATP releases this energy inside your cells, it’s called ATP hydrolysis. The amount of energy released can be measured in kilocalories, through an equation called the change in Gibbs free energy (ΔG). In this context, ΔG represents the kilocalories released by each individual molecule of  ATP. Energy Yield of Glucose One molecule of glucose makes about 30-34 molecules of ATP. It was widely believed the yield was 36-38, but newer sources find that was an overestimation. [*][*][*] The official change in free energy (∆G) is -7.3 kcal/mol.[*][*] This means each molecule of ATP generates about 7.3 kilocalories.   The total energy released by one glucose molecule would be: 34 ATP*7.3 kilocalories = 248 kilocalories. Energy Yield of BHB One molecule of BHB makes around 21.5 molecules of ATP.[*] This is less than glucose, but remember it’s more efficient and creates fewer free radicals in the process. In addition, ketone-made ATP releases a higher number of usable kilocalories (∆G). There is no official ∆G for this ATP, but one of the first studies on the topic found a change in free energy of -13 kcal/mol, which was confirmed by follow up studies.[*][*][*][*][*][*] This means each ATP molecule generates 13 kilocalories, almost double than ATP from glucose. The total energy released by one BHB molecule would be: 21.5 ATP*13 kilocalories = 279 kilocalories. VERDICT Glucose yields more ATP molecules, but the total energy released by each ATP is lower than BHB. BHB creates fewer ATP molecules, but it’s cleaner and releases more total energy per ATP molecule. In the end, BHB can make just as much, or even more energy than glucose in a cleaner way. Here’s all you need to know about using BHB salts: WHAT ARE BHB SALTS OR EXOGENOUS BHB? There are two ways to get exogenous ketones in the market: BHB salts and ketone esters. Ketone esters are the raw form of BHB, with nothing else added. However, this supplement is expensive, tastes terrible, and can affect the gastrointestinal system.[*] Enter: BHB salts. BHB salts are a novel and effective supplement created in a lab to help people enter and sustain ketosis. They’re a mix of: Exogenous BHB Mineral salts such as potassium, calcium, sodium, or magnesium, or amino acids like lysine and creatine The mineral salts added to exogenous BHB help to: Buffer the intensity of the free fatty acids Improve taste Lower the incidence of stomach issues Make it mixable with food and drinks When you take BHB salts, they’re broken down during digestion and release free BHB into your bloodstream. BHB then travels toward your organs, where it starts ketolysis to create energy. Basically, you enjoy the perks of BHB right away without having to wait for your body to raise ketone levels.   Don’t be afraid of salts like sodium. While it’s true excess sodium is harmful, people on a ketogenic diet can benefit from consuming more mineral salts because ketones make you lose more electrolytes in your urine. It’s recommended that keto-ers add more electrolytes to their food, such as sodium, calcium, potassium, and magnesium. BHB salts can help with that supplementation. HOW EXOGENOUS BHB SALTS ARE MADE Exogenous BHB salts are made in a lab from the fermentation of bacteria. Here’s how it happens: #1. Formation of PHB: PHB (or poly-beta-hydroxybutyrate) is where BHB comes from. PHB is a biodegradable polymer — a large biological molecule made of tiny molecules bonded together. It’s created by fermenting the bacteria acetobacter and Rhizobium in vitro.[*][*] #2. From PHB to BHB: PHB then goes through hydrolysis. This means adding water to cut the chemical bonds, which creates BHB.[*] #3. Adding mineral salts: For easier absorption, free BHB is mixed with a combination of salts, including sodium, potassium, calcium, magnesium, lithium, or amino acids like lysine, histidine, creatine, or arginine in different ratios. The specific salts and their quantities depend on the manufacturer.[*] Perfect Keto Exogenous Ketones are based on calcium, sodium, and magnesium. 5 BENEFITS OF TAKING EXOGENOUS BHB SALTS If you’re on the fence about taking BHB salts, here’s all they can do for you, in a nutshell: #1: PUTS YOU IN KETOSIS FAST BHB salts boost your BHB levels to over 1 mmol/L in less than 2 hours.[*][*] This is at least 85% faster than the usual 12+ hours it takes your body to start raising ketone levels on its own. In addition, the peak in BHB levels lasts almost 2 hours. This accelerated ketone production saves you from the dreaded keto flu. #2. DECREASES “KETO FLU” SYMPTOMS When people switch to a ketogenic diet for the first time, they may experience symptoms similar to the flu, including brain fog, irritability, nausea, cravings, stomach aches, and sore muscles. This happens because your body has to adjust to burning fatty acids, and it takes time. The severity of the symptoms varies from person to person. With BHB salts, you can skip the side effects of this adaptation because you enter ketosis almost immediately.   #3. NORMALIZES BLOOD SUGAR LEVELS BHB salts can lower blood sugar within the first 30 minutes of taking them and maintain that drop for hours.[*][*] One 4-week study found supplementing with BHB salts (of sodium and potassium) kept glucose low for 12 hours, in the range of 80-100 mg/dL. For reference, healthy people have a blood sugar of 72-108 mg/dL when fasting.[*] People with a low blood sugar tend to be more insulin sensitive, which prevents insulin resistance and the metabolic diseases that stem from it (obesity, type I diabetes, metabolic syndrome). #4. INCREASES FAT BURNING Taking BHB salts may decrease abdominal fat and accelerate the fat loss rate during workouts. One study found that abdominal fat cells got 30% smaller after supplementation with BHB salts. [*] Another study done on healthy males who exercised at least 3 times per week, but weren’t athletes, discovered that supplementing with ketone salts before doing aerobic exercise increased fat burning by 23%.[*] This fat loss is no surprise considering endogenous BHB also pushes your body to burn more fat for fuel. #5. MAY HELP LOWER ANXIETY New research finds that supplementing with ketone salts decreases anxiety-related behavior in rats. BHB salts can also make the brain more resistant to stressors that worsen behavioral performance.[*] This effect fits with the anti-depressive and anti-anxiety effect of endogenous ketones, although more human trials are needed.[*][*] There’s no doubt exogenous BHB allows you to tweak your metabolism in a way you couldn’t do just a few years ago. It basically lets you enter ketosis on command. Still, there’s one more thing you can do to make BHB salts more effective: Add MCT oil. Studies find that supplementing with a mix of BHB salts and MCTs skyrockets BHB production. KILLER COMBO: BHB SALTS + MCTS Taking BHB salts with MCTs raises blood BHB higher than salts or MCTs alone. Take a look: Source This graph, taken from a patent by the keto experts and researchers Dominic Paul D’Agostino, Patrick Arnold, and Shannon Kesl, shows that supplementing with a mix of BHB salts and MCTs drove blood BHB to a maximum of 1.33 mmol/L in just one hour. In contrast, BHB salts alone increased BHB to a maximum of 0.93 mmol/L, while MCTs increased it to a maximum of 0.53 mmol/L in a similar timeframe. This combo can also be better at lowering blood sugar than BHB salts alone. A  4-week study showed that BHB salts + MCT kept blood sugar consistently lower than BHB mineral salts throughout the whole experiment.[*] So, if you want to run on BHB, you can get there effortlessly by adding some MCTs to your exogenous ketones– how easy is that? A great way to combine the two is in your morning coffee or in fat bombs like Perfect Keto Mocha Fat Bombs. There’s one more thing you can do to amplify the benefits of BHB salts: Fasting. CAN I TAKE BHB SALTS WHILE FASTING? Short answer: yes and it can accelerate ketosis. When you fast, your body starts to make BHB on its own, so taking exogenous ketones won’t put you out of fasting mode. They simply add to the BHB already in your body, which puts you in ketosis a lot quicker.   In the same patent by Dominic D’Agostino, they found that combining fasting with one dose of BHB salts + MCT raised blood BHB levels to a peak of 2.77 mmol/L after 60 minutes.[*] If you fast to enter ketosis, BHB salts will give you a serious boost. If you fast only for longevity or weight loss benefits, BHB salts are harmless. Because exogenous ketone salts are a novel supplement, the quality and composition vary drastically across brands. That’s why you must learn to spot high-quality BHB. HOW TO CHOOSE THE BEST BHB SALTS The quality of your BHB salts will depend on 3 things: The ratio of salts to exogenous ketones The distribution of mineral salts The additional ingredients that make the supplement more palatable Here’s how to evaluate these things when you’re shopping for exogenous BHB: #1. MORE BHB, FEWER SALTS A high-quality supplement maximizes the exogenous BHB and adds only the amount of mineral salts that is absolutely necessary. The most popular mineral salts used in the market are: sodium, potassium, magnesium, and calcium, and most supplements use three of them, although some still use only two. Check the label and make sure the quantity of each mineral salt is below 1g. A BHB salt blend rarely needs more than 1g per mineral to be effective. For example, the 3 minerals salts used in Perfect Keto Exogenous Ketones provide less than one gram each (0.68g sodium, 0.59g calcium, and 0.32g magnesium). If a product contains salts above 1g, it usually means the blend is unbalanced. Speaking of which… #2. GO FOR BALANCED SALTS Next, look for a proportionate balance of mineral salts. You don’t want one mineral doing all the heavy lifting. For example, if a product has 0.3g magnesium, 0.5g calcium, and 0.6g sodium, the salts are well distributed. If a product has 0.95g of sodium and 0.2g of magnesium, it’s unbalanced and not the best choice. #3. STAY AWAY FROM FILLERS Fillers and texture enhancers like guar gum, xanthan gum, and silica (also named silicon dioxide) are common in commercial exogenous ketone salts, and also completely unnecessary. To get the purest BHB salts, simply look for the part of the nutritional label that says “other ingredients” and get the product with the shortest list. For instance, Perfect Keto Exogenous Ketones in the Coffee flavor, only have 3 extra ingredients: stevia, citric acid, and ground coffee powder. #4. AVOID ARTIFICIAL FLAVORS AND CARBS Flavored BHB salts are a delicious way to boost ketones, but manufacturers can cut corners by adding high carb sweeteners and artificial flavors. Look for a blend flavored with real ingredients (avoid artificial flavors) and sweetened with natural zero-carb sweeteners like stevia or monk fruit. Perfecto Keto Exogenous Ketones come in 4 flavors: Chocolate Sea Salt, Peaches and Cream, Coffee, and Vanilla — and none of them have artificial flavors or high carb sweeteners.   HOW TO TAKE BHB SALTS The beauty of BHB salts is you can add them to snacks and drinks. Here are some ideas and recipes: Drinks: Paired with MCT Oil Powder for that extra BHB boost.   Heavily diluted in water. Smoothies. Try this Chocolate Sea Salt Smoothie. Hot coffee. Chocolate Sea Salt and Coffee BHB salts are a good match.   Cold coffee. Try this Perfect Keto Frappuccino Snacks: Fudgy bites. Try these Chocolate Sea Salt Peanut Butter Bites Fat bombs. Try these Perfect Keto Mocha Fat Bombs or Perfect Keto Peaches & Cream Fat Bombs Mousse. Try this Perfect Keto Chocolate Mousse Popsicles. Peaches and Cream or Vanilla BHB salts are a perfect fit. HOW TO CHECK YOUR BHB LEVELS The only way to know if you’re running on BHB is by testing the levels of BHB in your breath, urine, or blood If you’re just starting out, urine strips help you track your BHB levels easily. When you’re a more experienced keto-er and want to be extremely precise, move on to testing the ketone levels in your blood. The Precision Xtra meter is one of the highest quality meters out there. You’ll have to prick your finger each time, but you’ll get the most accurate results. Read this guide for more info on how to measure your blood BHB: How to Know If You’re In Ketosis: A Guide To Testing Ketone Levels ARE BHB SALTS SAFE? Taking BHB salts is safe, as seen by trials in humans and animals.[*] Most exogenous BHB supplements contain 11-16 grams of BHB, which is an effective dose that doesn’t cause any major side effects.[*] It’s not dangerous to supplement with BHB salts as long as your blood BHB remains at a level of nutritional ketosis (0.6-3 mmol/L). As always, consult with your doctor before taking a new supplement. BHB, DIABETES, AND DIABETIC KETOACIDOSIS Diabetic people may benefit from being on a ketogenic diet and taking exogenous ketones because BHB lowers blood sugar and improves insulin sensitivity. In patients with type 2 diabetes, a ketogenic diet may improve blood sugar regulation to the point they can reduce or discontinue their medications.[*] In patients with type I diabetes, ketosis can help to manage symptoms.[*] However, diabetics are at higher risk of developing diabetic ketoacidosis, which is an overproduction of BHB to toxic levels.   Diabetic ketoacidosis happens when blood ketones go above 3 mmol/L thanks to dangerously low levels of insulin. Usually, the body tries to fight this by producing excessive amounts of glucose (higher than 200 mg/dL), but the cells are unable to process it due to lack of insulin. Diabetic ketoacidosis can be lethal. Some of the symptoms include: nausea, vomiting, abdominal pain, fatigue, confusion, and shortness of breath. Ketoacidosis happens mostly to diabetic patients, though, so if you’re non-diabetic your chances of getting it areextremely low. If you have diabetes, only try a new diet and new supplements under the supervision of your physician. BHB, ALCOHOL CONSUMPTION, AND ALCOHOLIC KETOACIDOSIS There’s a second form of BHB toxicity called alcoholic ketoacidosis, which is even less common than diabetic ketoacidosis. This happens when excessive alcohol consumption leads to depleted glucose stores and high ketone levels. Ethanol blocks your ability to use glucose, reduces insulin levels, and stimulates the breakdown of fats, leading to more ketones than you can handle.   This is easily avoidable by not drinking on an empty stomach and avoiding excessive drinking. BHB AND WOMEN The ketogenic diet doesn’t imbalance women’s hormones, so exogenous BHB is unlikely to do it either. However, if you have pre-existing hormone imbalance such as hyperthyroidism or PCOS, you should consult with your doctor before embarking on the ketogenic diet or taking any BHB supplements to make sure they don’t worsen your condition. For pregnant women, a ketogenic diet isn’t dangerous and ketosis often occurs naturally. With that said, there is just not enough data yet about the safety of taking exogenous ketones during pregnancy. Always consult with your doctor before taking a new supplement while pregnant. BHB AND CHILDREN Children can also benefit from a ketogenic diet. In fact, infants use ketones in their early days of life, so it’s not unsafe for the little ones to run on BHB from time to time. However, there’s not enough evidence about the safety of BHB salts in children. All the current studies on the topic have been made on adults. If you want your child to enjoy some of the benefits of keto, stick to kid-friendly keto recipes.   Run On Clean Energy BHB is far more efficient than glucose. Not only does it provide as much or even more energy, but it does so while fighting oxidative damage, lowering inflammation, and improving the function of your organs. If you want to burn more fat, increase cognitive function, and extend your lifespan, running on BHB is the way to go. You can optimize your BHB production by following a ketogenic diet, fasting, avoiding hidden carbs, and takingexogenous ketones and MCT oil. Exogenous ketones in the form of BHB salts boost your blood BHB in just an hour, so you don’t have to wait the 12+ hours it takes your body to completely switch between fuels. If you’ve been relying on carbs for energy — as most people do — but don’t feel your best, running on BHB can be just what your brain and metabolism need.
    128 Posted by Sarah Peterson
  • Original article: https://www.perfectketo.com/what-is-betahydroxybutyrate-or-bhb/   If you had to choose between: An inefficient fuel that  leaves a trail of smoke and slowly damages your car A clean fuel that gives you more mileage and keeps your car running smoothly It’s a no-brainer to pick option B, right? Well, you have to make that same decision when it comes to the fuel your body runs on, and guess what? Most people pick option A every day. The human body can choose between two different fuels: glucose (from carbs) and ketone bodies (from fat).   One ketone body called BHB is the clean and effective fuel your body can use for energy, yet you probably didn’t hear about it at school… or anywhere, really. That’s about to change. This article will break down everything you never knew you needed to know about BHB (and why it’s the fuel your body has been missing out on): What Is Beta-Hydroxybutyrate (BHB)? When BHB Is Necessary Types of BHB How Your Body Makes and Uses BHB BHB vs. Glucose 10 Reasons Beta-Hydroxybutyrate (BHB) Is a Rockstar Fuel How to Optimize BHB Levels What Are BHB Salts or Exogenous BHB? How Exogenous BHB Salts Are Made 5 Benefits of Taking Exogenous BHB Killer Combo: BHB Salts + MCTs Can I Take BHB Salts While Fasting? How to Choose The Best BHB Salts How to Take BHB Salts How to Check Your BHB Levels Are BHB Salts Safe? WHAT IS BETA-HYDROXYBUTYRATE (BHB)? Beta-hydroxybutyrate (BHB), is one of the three ketone bodies (energy molecules) your body makes when it’s running on fat instead of carbs. It’s also known as 3-hydroxybutyric acid or 3-hydroxybutanoic acid (3HB)[*]. The three main ketones your body makes from fatty acids are: Beta-hydroxybutyrate (BHB). This is the most abundant, making up to 78% of total ketones in the blood[*]. Acetoacetate (AcAc). It makes up around 20% of ketones in the blood. Acetone. The least abundant, making about 2% of ketones in the blood. It’s not used for energy. Both BHB and acetone are derived from acetoacetate (AcAc), however, BHB is the main ketone used for energy because it’s extremely stable and abundant, while acetone is lost through respiration and sweat. Your body makes two types of BHB[*][*]: D-BHB: This is the one your cells use for efficient energy and its produced in high amounts. It’s responsible for the anti-aging effects of total BHB. L-BHB: This one is produced in lower quantities and can’t be used for energy as efficiently as D-BHB. It’s more helpful in the synthesis of fatty acids. Ketosis is the metabolic state of using ketones — both BHB and AcAc — for energy instead of glucose. If you’re wondering — why would I need to switch fuels? The answer is simple: BHB works better. It’s not unnatural or harmful — in fact, it’s the opposite. 10 REASONS BETA-HYDROXYBUTYRATE (BHB) IS A ROCKSTAR FUEL BHB has more advantages beyond efficient energy production. It can supercharge your metabolism in ways glucose can’t. Here are just 10 reasons to make the switch: #1: ENHANCES GENE EXPRESSION A lot of the benefits of BHB come from its ability to optimize the expression of your genes, aka the way your cells interpret DNA instructions. That’s why we’re starting with it. Quick DNA function refresh: DNA is the biological code that specifies how organisms grow, function, and reproduce, which rarely changes. DNA expression is simply how well this code is passed down to your cells, which can vary depending on several factors.   You can think of DNA as the assembly instructions for building an IKEA chair, and DNA expression how well you interpret them to actually build the chair. If DNA expression is impaired (you can’t understand the instructions), your cells can’t create the proteins they need to survive. DNA expression involves two steps: Transcription: The DNA instructions for making a specific protein are copied into a messenger molecule called mRNA (think of printing your chair instructions). Translation: The mRNA is read and used to assemble the correct amino acids that form the protein (think of reading the instructions to assemble your chair). BHB improves gene expression by inhibiting molecules that silence important proteins[*].  It makes helpful genes available for expression, including FOXO and MTL1. The FOXO genes regulate oxidative stress resistance, metabolism, cell cycle, and apoptosis, which influences longevity and lifespan. MLT1 can help reduce toxicity[*]. Takeaway: BHB improves gene expression by unlocking important proteins that increase longevity and antioxidant protection. #2: SUPERCHARGES COGNITIVE FUNCTION Ketones are able to cross the blood-brain barrier easily and provide your brain with over 70% of its energetic needs[*]. This is possible because your brain becomes extremely receptive to ketone bodies when there’s not enough glucose around. In fact, neurons consume a lot of BHB, at a rate of 0.032 mmol/kg/min[*]. This quick absorption improves brain function in many ways, including: Preservation of neurons and synapses — which improves memory, focus, attention, and learning. Fewer free radicals Lower neuroinflammation Lower risk of dementia Reduced risk of depression and mood disorders Improved cognition in people with dementia, including those with  Alzheimer’s and Parkinson’s disease[*]. In one study, an increase of BHB in the brain 90 minutes after ingesting MCT oil improved paragraph recall in adults with impaired memory[*]. Preliminary studies also show ketones can improve working memory in both young and old subjects[*][*]. Another study found BHB has antidepressant and antianxiety-like effects because it prevents neuroinflammation in the hippocampus[*]. Multiple studies suggest BHB may be beneficial in preventing neurodegenerative diseases, including Huntington’s disease, Parkinson’s disease, and Alzheimer’s disease by improving mitochondrial respiration, preventing the accumulation of a toxic molecule called amyloid-β, and preventing brain atrophy[*]. BHB also protects the central nervous system by preserving an important type of cell present in the brain and spinal cord called ramified microglia, which acts as a sensor scanning for potential threats and protects neurons[*][*]. Takeaway: Your brain can absorb ketones quickly, and ketones protect neurons, synapses, lower neuroinflammation, and prevent neurodegeneration.    #3: KILLS INFLAMMATION BHB blocks a platform responsible for inflammation called NLRP3 inflammasome[*][*]. NLRP3 unleashes inflammatory molecules that trigger neuroinflammation, cancer, insulin resistance, bone diseases, Alzheimer’s disease, skin diseases, metabolic syndrome, type 2 diabetes, and gout[*]. Research shows BHB can destroy these inflammatory molecules: In one study, BHB administration decreased the inflammatory molecules IL-1β  and TNF-α in the hippocampus[*]. Another study showed BHB reduced the inflammatories interleukin IL-1β and IL-18 in human white blood cells[*]. This anti-inflammatory power makes BHB useful for preventing diseases triggered or aggravated by inflammation. For example, it may help treat inflammatory skin diseases like acne, psoriasis, varicose ulcers, allergic reactions, and skin photosensitivity[*]. Takeaway: BHB blocks the activity of the complex NLRP3 inflammasome, which is responsible for major inflammation in the body. #4: FIGHTS OXIDATIVE STRESS Remember that turning BHB into energy improves antioxidant protection by increasing the NAD+/NADH ratio and unlocking antioxidant genes? These protective effects are far-reaching. Evidence finds BHB can prevent and reverse oxidative damage in the brain (neurons, hippocampus, neocortex) and blood: One study found BHB prevented neuronal death. [*] In the hippocampus, — the part of your brain that regulates emotions, long-term memory, and spatial navigation — BHB protects the integrity of neuron synapses against oxidative damage. [*] In the neocortex, — the brain area responsible for higher-order functions like cognition, spatial reasoning, language, and sensory perception —  BHB protects neurons from oxidation. [*] In endothelial cells (cells lining the inside of your blood vessels), ketones activate antioxidant defenses, which protects the cardiovascular system. [*] Another study done on athletes found ketone bodies reduced the oxidative stress caused by exercise. [*] Takeaway: The antioxidant effects of manufacturing BHB protect your cells against oxidative damage, especially in the brain. > #5. INCREASES LIFESPAN BHB can help you live a longer, healthier life thanks to: Its positive effects on gene expression Its anti-inflammation powers (as explained before). Basically, BHB unlocks helpful genes that work together to fight oxidative stress and improve metabolism, increasing longevity. [*] This is how BHB taps into your anti-aging genes: Blocks the insulin-like growth factor (IGF-1) receptor gene. This gene’s role is boosting cell growth and proliferation, but excessive growth is linked to diseases and early death. A lower activity of IGF-1 delays aging and increases lifespan.[*] Activates FOXO genes. One gene in particular, FOXO3a, is linked to increased longevity in humans because it boosts antioxidant creation.[*] Since BHB also suppresses inflammation, it prevents age-related inflammatory diseases that cause functional decline and early death, including arthritis and bone loss. [*] Takeaway: BHB can increase lifespan by activating anti-aging genes and slashing inflammation. #6. HELPS FIGHT AND PREVENT CANCER BHB can slow down the growth of tumors because cancer cells can’t use ketones well enough to grow and spread. This phenomenon is explained by Warburg’s effect, which says cancer cells and tumors depend on glucose breakdown (glycolysis) to grow, in contrast to healthy cells that can use either glucose or ketones.[*] Scientists exploited this weakness by taking away glucose and forcing cancer cells to depend on ketones, and it actually decreased tumors in many organs including the brain, pancreas, and colon, because the cells were unable to spread. Here’s what different studies have found: Ketones slowed down brain tumor growth by lowering blood glucose and IGF-1 (two factors that encourage tumor progression).[*] In other words, when ketones replaced glucose as fuel, brain tumors shrank. Ketones stopped the spread of metastatic cancer cells both in vivo and in vitro.[*] Ketone bodies killed pancreatic cancer cells and diminished cachexia. Cachexia is a syndrome that up to 80% of people with advanced cancer have, and consists of extreme weight loss, fatigue, and muscle atrophy.[*] Ketones also slowed down the growth neuroblastomas, cancer cells that form in nerve tissue.[*] Takeaway: Running on BHB impairs the growth of tumors. #7. BOOSTS INSULIN SENSITIVITY Ketones improve insulin sensitivity by reducing insulin levels as well as blood glucose and mimicking the effects of insulin.[*][*] This can reverse insulin resistance — what happens when your body is forced to make extra insulin to deal with blood sugar. When you’re sensitive to insulin, you’re at a lower risk of metabolic diseases such as type 2 diabetes, non-alcoholic fatty liver disease, and obesity. Takeaway: BHB can improve insulin sensitivity and reverse insulin resistance by keeping glucose and insulin levels low. #8. OPTIMIZES HEART FUNCTION Did you know that your heart’s preferred energy source are long-chain fatty acids? In the normal adult heart, fatty acids provide up to 70% of the ATP,  while glucose, lactate, amino acids, and ketones supply the rest.[*] Note: Using fats and using ketones are not the same thing. The heart metabolizes fat directly, without turning it into BHB first. However, just like the brain, your heart can adapt extremely well to ketones if needed. It automatically learns to regulate the breakdown of ketones, thanks to the remarkable metabolic flexibility of heart cells. Burning BHB is more energetically efficient for the heart than using fatty acids because: BHB improves its mechanical efficiency and blood flow. Burning fatty acids increases free radicals, while BHB destroys them. Studies found the mechanical efficiency of the heart increased by 30% and blood flow increased by 75% when running on ketones.[*][*][*] Takeaway: BHB is a better fuel for the heart. It protects against oxidative damage, enhances mechanical efficiency, and improves blood flow. #9: BOOSTS FAT LOSS AND WORKOUT PERFORMANCE Your skeletal muscle also benefits from BHB, especially when exercising. Exercise increases the absorption of ketones dramatically, and in turn ketones improve performance and recovery. It’s a cycle of goodness. In short, ketones can: Improve performance during endurance exercises (cycling, hiking, dancing, swimming, power yoga, playing sports, or walking long distances) Increase fat loss without reducing muscle mass in resistance exercises Increase fat burning Replenish glycogen stores and accelerate recovery Endurance exercises in particular accelerate the absorption of BHB. One study found the rate of ketone consumption increased three to five fold during 30 min of cycling exercise. Ketones ended up providing 85–125 kJ of energy over 30 min of exercise, compared to just 27 kJ during 30 min of rest.[*] This increased absorption triggers more fat burning. One study found the burning of intramuscular fat jumped 20-fold during exercise on ketosis, even when there was muscle glycogen available. This means the cells ignored the usually-preferred glucose reserves and burned more fat instead.[*][*] This leads to accelerated fat loss. People who do resistance training on ketosis lose fat mass quicker, without losing lean muscle.[*][*] Thanks to this focus on fat, the body is able to replenish glycogen quicker after a workout, which seriously improves recovery. One study found that when BHB levels increased, both glycogen and glucose uptake rate also increased after a workout. This is a big deal because your muscles can only use glycogen for recovery.[*] Lastly, ketones can decrease fatigue and improve cognitive function when exercising.[*] Takeaway: Exercises accelerates the absorption of BHB, and BHB boosts fat burning, recovery, and energy. #10: PREVENTS BONE DETERIORATION BHB has impressive bone preserving abilities. Research finds it can prevent bone degradation by stopping the production of cells called osteoclasts in subjects with osteoporosis.[*][*] You’ve probably heard of osteoblasts, which are cells that produce the matrix for bone formation.They create bones. Osteoclasts are the exact opposite. Their name comes from the words “osteon” (bone) and “clastos” (broken). Their job is to break down bone tissue, which is helpful in bones of healthy people, but terrible in people with osteoporosis and other bone diseases.   By stopping osteoclasts, BHB reverses and possibly prevents bone break down. It can also strengthen your bones. One study[*] found BHB: Prevented bone density decline Increased resistance to bone deformation Boosted the strength of the femur Improved the volume of the internal tissue of the bone (called cancellous or spongy bone) Takeaway: BHB prevents the growth of cells that break down bone tissue and increases bone strength and resistance. Now that you’re up to speed with the perks of running on BHB, here’s how to make sure you’re making enough of it: HOW TO OPTIMIZE BHB LEVELS Swapping glucose for BHB is extremely beneficial, but our food environment makes it a challenge. These 4 things will help you maintain consistent levels of ketones: #1: FOLLOW A KETOGENIC DIET Starting a ketogenic diet is the first thing you should do if you’re serious about running on ketones. Mistakenly, the ketogenic diet is often lumped with other low carb diets, but keto is the only diet that changes your metabolism from burning sugar to burning fat. Its recommended macros of 70-80% fat, 20-25% protein, and 5-10% carbs are designed to make your body produce more BHB and AcAc so you can enter and remain in nutritional ketosis. You can expect your blood ketones to stay between 0.6 and 3.0 mmol/L. Here’s the gist of what you can eat on the ketogenic diet: Healthy fats: Avocado, coconut oil, MCT oil, avocado oil, walnut oil, olive oil. Dairy: cream cheese, cheeses, sour cream, butter, ghee. Cage-free eggs. Red meats: grass-fed beef, organs, game meat, lamb, bison, pork. White meats: pastured chicken, turkey, duck. Fish and seafood: Especially fatty fish like mackerel, sardines, and salmon. Nuts and seeds: Nut butter, macadamia nuts, cashews,  walnuts, almonds, chia seeds, flaxseed. Low-starch veggies: Spinach, kale, lettuce, collard greens, zucchini, tomato. Low glycemic fruits (in small quantities if at all): blueberries, strawberries, cherries. Keto-friendly snacks: Low-carb cookies, flourless pancakes, keto frappuccino. Yes, being on keto means you’ll have to brush up on your cooking skills a little bit, but it’s not hard to cook keto meals (few ingredients!) and you’ll feel amazing afterward. For more info on what to eat, what to avoid, and what recipes to make, read these: The Ultimate Start Up Guide to The Ketogenic Diet Full Ketogenic Diet Food List Keto Fruit: The Essential Guide to Nature’s Candy on a Low Carb Diet Ketogenic Diet Foods to Avoid: 108 Foods That’ll Slow Your Fat Loss Keto Recipes for Breakfast, Lunch, Dinner, and Dessert Find out your personal macros with the Keto Calculator. #2. DO INTERMITTENT FASTING Doing intermittent fasting will help you enter or get back into BHB-burning mode quickly. Unlike regular fasting (not eating for several days), intermittent fasting is done for just a portion of the day, and it gives you the same cognitive and longevity benefits. There are several ways to do intermittent fasting, but the most common is to eat in a limited window of time during the day and fast the remaining hours. Usually, people fast for 16 hours a day and eat in an 8-hour window. For example, you could fast from 08:00 pm to 12:00 pm, and eat from 12:00 pm to 08:00 pm. Fasting this way will: Increase your BHB levels above 0.6 mmol/L Activate autophagy (the cleaning up of old cells) Support healthy weight loss If you combine a ketogenic diet with intermittent fasting, you’ll be able to run on ketones more easily. #3. AVOID HIDDEN CARBS Our food environment works hard to make us rely on sugar for energy. Carbs are hidden everywhere, in “healthy” snacks, beverages, and restaurant meals. If you’re not careful, you can surpass the small number of daily carbs you can eat on ketosis, which is around 30g. Want to know how easy it is to hit or pass your daily carb limit? A medium banana has 27g of carbs. A Nature Valley Oats ‘n Honey Crunchy Granola bar has 31g of carbs. A medium baked potato has 37g of carbs. One small buttered popcorn has 37g of carbs. A grande mocha Frappuccino with regular milk has 61g carbs.[*] If you eat too many carbs, your body will switch back to burning glucose, not BHB, and you will miss out on all the metabolic and cognitive benefits of ketones. Bummer. You can avoid eating excess carbs by: Sticking to real food. Avoid packaged snacks and drinks as often as possible. Always reading labels at the supermarket. Cooking at home more often. Googling what doesn’t have labels. If possible, check the nutrition facts for the places you frequent. Here are the nutritional facts of the menu from Starbucks, Red Lobster, Applebee’s, Outback Steakhouse, TGI Friday’s,Chipotle, Subway, and In-n-Out. Check more restaurants with MyFitnessPal. Avoiding fast food restaurants altogether. #4. TAKE BHB SALTS Of course, you could save yourself a lot of work and boost your BHB levels effortlessly by taking exogenous ketonesin the form of BHB salts. They will: Raise your BHB levels wickedly fast. Save you the 12+ hours it takes your body to increase BHB levels from scratch. Help you avoid the keto flu if you’re a beginner. BHB salts are completely safe and a total game changer if you want to reap the full benefits of ketosis. When you combine a ketogenic diet, intermittent fasting, and BHB salts, running on BHB is extremely easy. WHEN BHB IS NECESSARY The human body can efficiently burn BHB for energy because… We’ve been doing it for hundreds of thousands of years. It’s how our ancestors survived. Our bodies are literally born to do so. Let’s back up a bit: Humans in the hunter-gatherer era survived thanks to metabolic flexibility — the body’s ability to use different fuels for energy depending on the nutrients available. This adaptation was vital during a time when the source, quantity, and frequency of food was uncertain[*]. Most of the time, people were fasting, so their bodies ran on ketones, not glucose. Nowadays, most adults rely on glucose for energy thanks to the abundance of high carb foods, but we’re all born needing and using ketones. Children can produce and use BHB more efficiently than adults because, in the early days of life, ketones (BHB and AcAc) are better than glucose for brain growth and lung function. At this stage, blood ketones can reach 2–3 mmol/L (micromolar per liter), the same levels as in a ketogenic diet[*]. This ability is to burn ketones is never lost. Elderly people are able to generate ketones after a fast or a ketogenic meal at the same levels as younger adults. If we wanted, we could keep using ketones for energy throughout our adult life like we did as infants. Sadly, our food environment pushes us to ditch ketones and rely on glucose when we grow up. Unless you’re a baby, a regular keto-er, a carnivore, diabetic, or a caveman, your body runs on glucose. The good news is, it’s easy to start using ketones for fuel again. Your body is always making BHB and AcAc, but on a regular carb-based diet, the levels remain below 0.5 mmol/L (micromolar per liter), which isn’t enough to fuel your cells. Only certain conditions[*][*] can boost BHB levels high enough to make the fuel switch: Following a ketogenic diet. On low carb, high fat ketogenic diet, your body will produce consistent ketone levels above 2 mmol/L. Fasting. BHB levels rise above 0.6 mmol/L after 12–16 hours of fasting and reach 1–2 mmol/L after 2 days of fasting. Doing Intense Exercise. Doing intense exercise for 90 minutes can boost BHB to 1–2 mmol/L. In these three circumstances, your body doesn’t have access to enough carbs (glucose) or stored glucose (glycogen), so it turns to stored fat for energy. The fatty acids are metabolized by your liver into ketones (mostly BHB), which can be used by your cells as an efficient fuel source. When your ketone levels are consistently between 0.6 and <3 mmol/L, you’re in nutritional ketosis, which has many advantages, including: Increased cognitive function (clearer thinking, higher focus) Stable blood sugar More energy Healthy weight loss Accelerated fat loss Better workout performance During therapeutic treatments under the supervision of a physician, your blood BHB may rise up to 10 mmol/L. There are other circumstances that push your body to make more ketones, but these are detrimental to your health and should not be attempted: Not monitoring insulin levels as a diabetic. If insulin levels are not controlled in diabetic patients, they can drop dramatically and make your body overproduce ketone bodies above 3 mmol/L. This may provokeketoacidosis, which can be lethal (more on that later). Entering starvation mode after extended fasts. Prolonged starvation will increase ketones to  6–8 mmol/L, but it’s not the healthiest approach. What’s the point of making lots of efficient BHB if you’re going to starve yourself and miss out on important nutrients? Remember, being in ketosis doesn’t mean you’re healthy. The best way to reap all the health benefits of BHB is to keep it in the range of nutritional ketosis. The three types of cells that consume the most BHB are: Cardiomyocytes (cardiac muscle cells). The heart is the highest ketone body consumer per unit mass[*]. Skeletal myocytes (skeletal muscle cells). Neurons. Normally, your brain and muscles rely heavily on glucose, while your heart burns long-chain fatty acids, but switching to BHB can enhance their function and provide extra protection against disease. THE TWO TYPES OF BHB Your body can use two forms of BHB: endogenous and exogenous. Endogenous BHB is the one your body makes by itself. “Endo” comes from the Greek éndon, which means “within”. Exogenous ketones are external BHB molecules you can take as a supplement to kickstart ketosis quickly, usually in the form of BHB salts or esters. “Exo” is the opposite of “endo” and means “external”. This article will discuss both of them. Let’s start by looking at how your body manufactures endogenous BHB from scratch: HOW YOUR BODY MAKES AND USES BHB The cycle of turning fats into BHB, and then BHB into energy, involves two processes: Ketogenesis: The production of BHB in the liver. It means ketone (keto-) generation (-genesis). Ketolysis: The process of transforming BHB into ATP (the energy currency of the cell). It means ketone (keto-) breakdown (-lysis). Both mechanisms involve complex chemical processes which are condensed below[*][*][*][*][*][*]: STEP #0: MAKING FREE FATTY ACIDS (LIPOLYSIS) Before BHB production begins, stored fat needs to be converted into free fatty acids.   Lipolysis is the process of turning triglycerides — stored in fat tissue — into glycerol and free fatty acids (FFA) that enter the blood and travel to the liver to be turned into BHB. PROCESS #1: KETOGENESIS Where: The mitochondria of liver cells Result: BHB BHB production happens in the mitochondria of liver cells (what is commonly known as the powerhouse of the cell), and it follows these steps: #1. Fatty acid activation (acyl-CoA): Before they’re able to cross the mitochondrial barrier, long-chain fatty acids need to be “activated” because the mitochondria only accepts short-chain fats. A molecule called Coenzyme A (CoA) is attached at the end of the fatty acid, and this combo is called acyl-CoA. #2. Fatty acid oxidation (acetyl-CoA): Once inside the mitochondria, acyl-CoA is broken down into acetyl-CoA.This a crucial molecule because it’s the only one that can enter the Krebs Cycle: #3. Krebs Cycle: Also known as the citric acid cycle (CAC) or tricarboxylic acid (TCA) cycle. This is the process that generates ketones and precursors of amino acids by breaking down acetyl-CoA. It works by fully oxidizing all molecules to carbon dioxide (CO2). The process for making BHB goes like this: Acetyl-CoA Acetoacetyl-CoA: acetyl-CoA degrades into acetoacetyl-CoA. HMG-CoA: Acetoacetyl-CoA degrades into HMG-CoA. Acetoacetate (AcAc): HMG-CoA turns into the first ketone, AcAc. BHB: AcAc is reduced to BHB, and acetone is produced as a by-product. PROCESS #2: KETOLYSIS Where: The mitochondria in cells of other organs except the liver Result: ATP Once BHB is released (ketogenesis), your heart, brain, and other organs absorb it to turn it into ATP — the energy currency. It will go through the Krebs cycle again, just a little differently: #1. Absorption by organs: When BHB is in the bloodstream, your organs — except your liver — take it up for energy. Ironically, the liver doesn’t have the ability to utilize ketones even though it makes them[*].   #2. Turning BHB back to acetyl-CoA: BHB has to turn back into acetyl-CoA because it’s the only molecule that can go through the Krebs cycle, remember? So, when BHB enters other organs, it retraces the steps it first took in the liver: BHB Acetoacetate (AcAc): BHB turns back into the first ketone. Acetoacetyl-CoA: Acetoacetate (AcAc) is turned back to this molecule. Acetyl-CoA: Acetoacetyl-CoA turns back to acetyl-CoA, which can enter the Krebs cycle. #3. Krebs Cycle: Acetyl-CoA completely oxidizes in the cycle, and this oxidation releases electrons into two carrier molecule: NADH or FADH2. #4. Oxidative phosphorylation (aka ATP creation): The electrons from NADH or FADH2 are transferred towards O2, which creates ATP. This is also called the mitochondrial respiratory chain. As you can see, using BHB for energy is an intricate process. Basically, acetyl-CoA can turn into BHB (in the liver), and then BHB has to turn back into acetyl-CoA to make usable energy (ATP in organs). In summary, BHB is created in the liver by oxidizing fats (ketogenesis). Then BHB is turned into ATP (energy) through oxidation in organs (ketolysis). Running on BHB gives you a metabolic advantage over glucose.   BHB VS. GLUCOSE AS FUEL If you’re curious to know exactly how BHB compares to glucose in terms of energy, here’s a breakdown of their: Energy Efficiency Energy Yield ENERGY EFFICIENCY Creating energy generates harmful by-products called free radicals, or oxidants. These molecules can damage cells and DNA, and they’re inevitable. During the production of ATP, the oxidants O2∙− and H2O2 are leaked. These are “tamer” free radicals that can be easily countered with antioxidants. However, under the wrong circumstances, they have the potential to run wild and turn into the most damaging free radicals: reactive nitrogen species (RNS) and hydroxyl radical (∙OH), which are responsible for most oxidative damage.[*] Therefore, it’s necessary to minimize free radicals during energy production and optimize antioxidants. The fuel your body uses and the resources they consume to create ATP influences how many free radicals are created and suppressed. The fewer free radicals a fuel creates, the more efficient it is. Glucose Efficiency Glucose goes through a slightly longer process than BHB before entering the Krebs cycle. Through glycolysis, glucose turns into pyruvate, and then pyruvate is turned into acetyl-CoA, which can enter the Krebs cycle. This path from glucose > pyruvate > acetyl-CoA eats up significant resources. One glucose molecule consumes 4 NAD+ molecules, which turn into 4 NADH. The ratio of NAD+/NADH matters because it regulates oxidant and antioxidant activity: NAD+ is the “good” molecule. It protects against oxidative stress, especially the oxidant H2O2, and improves autophagy (cleaning up damage cells). NAD+ is consumed as fuel for chemical reactions (like ATP production) and turns into NADH.[*] NADH is also necessary, mainly to produce ATP, but it doesn’t protect against damage. When there’s more NADH than NAD+, more free radicals are produced and helpful enzymes are inhibited.[*] In other words, the ratio of NAD+/ NADH should stay high. Low NAD+ causes serious oxidative damage. Because glucose consumes 4 NAD+ molecules from the get-go, it tips the scale towards more NADH, which can cause more oxidative damage.   BHB Efficiency BHB skips glycolysis. It only has to convert back to AcAc and then to acetyl-CoA before entering the Krebs cycle, a process that uses up half the resources as glucose. One BHB molecule consumes only 2 NAD+ molecules, which turn into 2 NADH. This means BHB is more efficient than glucose and protects the NAD+/NADH ratio. In fact, research[*] shows BHB not only preserves but increases the NAD+/NADH ratio, which can: Protect against oxidative stress and oxidants created during energy production Support mitochondrial function and biogenesis Provide anti-aging and longevity effects Increase the amount of free NAD+ than can be used for optimal gene expression BHB also reduces free radicals through protective proteins that only activate when your body runs on ketones: UCP: Fats accelerate the activity of the UCP protein. UCP kills the free radicals that leak during the creation of energy, preventing oxidative damage in the mitochondria.[*][*] SIRT3: When your body switches from glucose to fats, a protein called Sirtuin 3 (SIRT3) increases. It activates a powerful antioxidant called of MnSOD and other mitochondrial antioxidant systems to keep oxidants low during energy creation. It also stabilizes the FOXO genes, which protect against oxidation.[*] VERDICT Using BHB for fuel is more efficient than using glucose because it consumes less NAD+ molecules, increasing the NAD+/NADH ratio, which prevents oxidative damage and promotes longevity. It also fights the damage of inevitable free radicals by activating powerful antioxidants, which glucose doesn’t do. Energy Yield The energy yield is measured by two things: Number of ATP molecules created per molecule of BHB or glucose Usable energy from each ATP molecule Each molecule of glucose and BHB creates different amounts of ATP, which carries usable energy to your cells. When ATP releases this energy inside your cells, it’s called ATP hydrolysis. The amount of energy released can be measured in kilocalories, through an equation called the change in Gibbs free energy (ΔG). In this context, ΔG represents the kilocalories released by each individual molecule of  ATP. Energy Yield of Glucose One molecule of glucose makes about 30-34 molecules of ATP. It was widely believed the yield was 36-38, but newer sources find that was an overestimation. [*][*][*] The official change in free energy (∆G) is -7.3 kcal/mol.[*][*] This means each molecule of ATP generates about 7.3 kilocalories.   The total energy released by one glucose molecule would be: 34 ATP*7.3 kilocalories = 248 kilocalories. Energy Yield of BHB One molecule of BHB makes around 21.5 molecules of ATP.[*] This is less than glucose, but remember it’s more efficient and creates fewer free radicals in the process. In addition, ketone-made ATP releases a higher number of usable kilocalories (∆G). There is no official ∆G for this ATP, but one of the first studies on the topic found a change in free energy of -13 kcal/mol, which was confirmed by follow up studies.[*][*][*][*][*][*] This means each ATP molecule generates 13 kilocalories, almost double than ATP from glucose. The total energy released by one BHB molecule would be: 21.5 ATP*13 kilocalories = 279 kilocalories. VERDICT Glucose yields more ATP molecules, but the total energy released by each ATP is lower than BHB. BHB creates fewer ATP molecules, but it’s cleaner and releases more total energy per ATP molecule. In the end, BHB can make just as much, or even more energy than glucose in a cleaner way. Here’s all you need to know about using BHB salts: WHAT ARE BHB SALTS OR EXOGENOUS BHB? There are two ways to get exogenous ketones in the market: BHB salts and ketone esters. Ketone esters are the raw form of BHB, with nothing else added. However, this supplement is expensive, tastes terrible, and can affect the gastrointestinal system.[*] Enter: BHB salts. BHB salts are a novel and effective supplement created in a lab to help people enter and sustain ketosis. They’re a mix of: Exogenous BHB Mineral salts such as potassium, calcium, sodium, or magnesium, or amino acids like lysine and creatine The mineral salts added to exogenous BHB help to: Buffer the intensity of the free fatty acids Improve taste Lower the incidence of stomach issues Make it mixable with food and drinks When you take BHB salts, they’re broken down during digestion and release free BHB into your bloodstream. BHB then travels toward your organs, where it starts ketolysis to create energy. Basically, you enjoy the perks of BHB right away without having to wait for your body to raise ketone levels.   Don’t be afraid of salts like sodium. While it’s true excess sodium is harmful, people on a ketogenic diet can benefit from consuming more mineral salts because ketones make you lose more electrolytes in your urine. It’s recommended that keto-ers add more electrolytes to their food, such as sodium, calcium, potassium, and magnesium. BHB salts can help with that supplementation. HOW EXOGENOUS BHB SALTS ARE MADE Exogenous BHB salts are made in a lab from the fermentation of bacteria. Here’s how it happens: #1. Formation of PHB: PHB (or poly-beta-hydroxybutyrate) is where BHB comes from. PHB is a biodegradable polymer — a large biological molecule made of tiny molecules bonded together. It’s created by fermenting the bacteria acetobacter and Rhizobium in vitro.[*][*] #2. From PHB to BHB: PHB then goes through hydrolysis. This means adding water to cut the chemical bonds, which creates BHB.[*] #3. Adding mineral salts: For easier absorption, free BHB is mixed with a combination of salts, including sodium, potassium, calcium, magnesium, lithium, or amino acids like lysine, histidine, creatine, or arginine in different ratios. The specific salts and their quantities depend on the manufacturer.[*] Perfect Keto Exogenous Ketones are based on calcium, sodium, and magnesium. 5 BENEFITS OF TAKING EXOGENOUS BHB SALTS If you’re on the fence about taking BHB salts, here’s all they can do for you, in a nutshell: #1: PUTS YOU IN KETOSIS FAST BHB salts boost your BHB levels to over 1 mmol/L in less than 2 hours.[*][*] This is at least 85% faster than the usual 12+ hours it takes your body to start raising ketone levels on its own. In addition, the peak in BHB levels lasts almost 2 hours. This accelerated ketone production saves you from the dreaded keto flu. #2. DECREASES “KETO FLU” SYMPTOMS When people switch to a ketogenic diet for the first time, they may experience symptoms similar to the flu, including brain fog, irritability, nausea, cravings, stomach aches, and sore muscles. This happens because your body has to adjust to burning fatty acids, and it takes time. The severity of the symptoms varies from person to person. With BHB salts, you can skip the side effects of this adaptation because you enter ketosis almost immediately.   #3. NORMALIZES BLOOD SUGAR LEVELS BHB salts can lower blood sugar within the first 30 minutes of taking them and maintain that drop for hours.[*][*] One 4-week study found supplementing with BHB salts (of sodium and potassium) kept glucose low for 12 hours, in the range of 80-100 mg/dL. For reference, healthy people have a blood sugar of 72-108 mg/dL when fasting.[*] People with a low blood sugar tend to be more insulin sensitive, which prevents insulin resistance and the metabolic diseases that stem from it (obesity, type I diabetes, metabolic syndrome). #4. INCREASES FAT BURNING Taking BHB salts may decrease abdominal fat and accelerate the fat loss rate during workouts. One study found that abdominal fat cells got 30% smaller after supplementation with BHB salts. [*] Another study done on healthy males who exercised at least 3 times per week, but weren’t athletes, discovered that supplementing with ketone salts before doing aerobic exercise increased fat burning by 23%.[*] This fat loss is no surprise considering endogenous BHB also pushes your body to burn more fat for fuel. #5. MAY HELP LOWER ANXIETY New research finds that supplementing with ketone salts decreases anxiety-related behavior in rats. BHB salts can also make the brain more resistant to stressors that worsen behavioral performance.[*] This effect fits with the anti-depressive and anti-anxiety effect of endogenous ketones, although more human trials are needed.[*][*] There’s no doubt exogenous BHB allows you to tweak your metabolism in a way you couldn’t do just a few years ago. It basically lets you enter ketosis on command. Still, there’s one more thing you can do to make BHB salts more effective: Add MCT oil. Studies find that supplementing with a mix of BHB salts and MCTs skyrockets BHB production. KILLER COMBO: BHB SALTS + MCTS Taking BHB salts with MCTs raises blood BHB higher than salts or MCTs alone. Take a look: Source This graph, taken from a patent by the keto experts and researchers Dominic Paul D’Agostino, Patrick Arnold, and Shannon Kesl, shows that supplementing with a mix of BHB salts and MCTs drove blood BHB to a maximum of 1.33 mmol/L in just one hour. In contrast, BHB salts alone increased BHB to a maximum of 0.93 mmol/L, while MCTs increased it to a maximum of 0.53 mmol/L in a similar timeframe. This combo can also be better at lowering blood sugar than BHB salts alone. A  4-week study showed that BHB salts + MCT kept blood sugar consistently lower than BHB mineral salts throughout the whole experiment.[*] So, if you want to run on BHB, you can get there effortlessly by adding some MCTs to your exogenous ketones– how easy is that? A great way to combine the two is in your morning coffee or in fat bombs like Perfect Keto Mocha Fat Bombs. There’s one more thing you can do to amplify the benefits of BHB salts: Fasting. CAN I TAKE BHB SALTS WHILE FASTING? Short answer: yes and it can accelerate ketosis. When you fast, your body starts to make BHB on its own, so taking exogenous ketones won’t put you out of fasting mode. They simply add to the BHB already in your body, which puts you in ketosis a lot quicker.   In the same patent by Dominic D’Agostino, they found that combining fasting with one dose of BHB salts + MCT raised blood BHB levels to a peak of 2.77 mmol/L after 60 minutes.[*] If you fast to enter ketosis, BHB salts will give you a serious boost. If you fast only for longevity or weight loss benefits, BHB salts are harmless. Because exogenous ketone salts are a novel supplement, the quality and composition vary drastically across brands. That’s why you must learn to spot high-quality BHB. HOW TO CHOOSE THE BEST BHB SALTS The quality of your BHB salts will depend on 3 things: The ratio of salts to exogenous ketones The distribution of mineral salts The additional ingredients that make the supplement more palatable Here’s how to evaluate these things when you’re shopping for exogenous BHB: #1. MORE BHB, FEWER SALTS A high-quality supplement maximizes the exogenous BHB and adds only the amount of mineral salts that is absolutely necessary. The most popular mineral salts used in the market are: sodium, potassium, magnesium, and calcium, and most supplements use three of them, although some still use only two. Check the label and make sure the quantity of each mineral salt is below 1g. A BHB salt blend rarely needs more than 1g per mineral to be effective. For example, the 3 minerals salts used in Perfect Keto Exogenous Ketones provide less than one gram each (0.68g sodium, 0.59g calcium, and 0.32g magnesium). If a product contains salts above 1g, it usually means the blend is unbalanced. Speaking of which… #2. GO FOR BALANCED SALTS Next, look for a proportionate balance of mineral salts. You don’t want one mineral doing all the heavy lifting. For example, if a product has 0.3g magnesium, 0.5g calcium, and 0.6g sodium, the salts are well distributed. If a product has 0.95g of sodium and 0.2g of magnesium, it’s unbalanced and not the best choice. #3. STAY AWAY FROM FILLERS Fillers and texture enhancers like guar gum, xanthan gum, and silica (also named silicon dioxide) are common in commercial exogenous ketone salts, and also completely unnecessary. To get the purest BHB salts, simply look for the part of the nutritional label that says “other ingredients” and get the product with the shortest list. For instance, Perfect Keto Exogenous Ketones in the Coffee flavor, only have 3 extra ingredients: stevia, citric acid, and ground coffee powder. #4. AVOID ARTIFICIAL FLAVORS AND CARBS Flavored BHB salts are a delicious way to boost ketones, but manufacturers can cut corners by adding high carb sweeteners and artificial flavors. Look for a blend flavored with real ingredients (avoid artificial flavors) and sweetened with natural zero-carb sweeteners like stevia or monk fruit. Perfecto Keto Exogenous Ketones come in 4 flavors: Chocolate Sea Salt, Peaches and Cream, Coffee, and Vanilla — and none of them have artificial flavors or high carb sweeteners.   HOW TO TAKE BHB SALTS The beauty of BHB salts is you can add them to snacks and drinks. Here are some ideas and recipes: Drinks: Paired with MCT Oil Powder for that extra BHB boost.   Heavily diluted in water. Smoothies. Try this Chocolate Sea Salt Smoothie. Hot coffee. Chocolate Sea Salt and Coffee BHB salts are a good match.   Cold coffee. Try this Perfect Keto Frappuccino Snacks: Fudgy bites. Try these Chocolate Sea Salt Peanut Butter Bites Fat bombs. Try these Perfect Keto Mocha Fat Bombs or Perfect Keto Peaches & Cream Fat Bombs Mousse. Try this Perfect Keto Chocolate Mousse Popsicles. Peaches and Cream or Vanilla BHB salts are a perfect fit. HOW TO CHECK YOUR BHB LEVELS The only way to know if you’re running on BHB is by testing the levels of BHB in your breath, urine, or blood If you’re just starting out, urine strips help you track your BHB levels easily. When you’re a more experienced keto-er and want to be extremely precise, move on to testing the ketone levels in your blood. The Precision Xtra meter is one of the highest quality meters out there. You’ll have to prick your finger each time, but you’ll get the most accurate results. Read this guide for more info on how to measure your blood BHB: How to Know If You’re In Ketosis: A Guide To Testing Ketone Levels ARE BHB SALTS SAFE? Taking BHB salts is safe, as seen by trials in humans and animals.[*] Most exogenous BHB supplements contain 11-16 grams of BHB, which is an effective dose that doesn’t cause any major side effects.[*] It’s not dangerous to supplement with BHB salts as long as your blood BHB remains at a level of nutritional ketosis (0.6-3 mmol/L). As always, consult with your doctor before taking a new supplement. BHB, DIABETES, AND DIABETIC KETOACIDOSIS Diabetic people may benefit from being on a ketogenic diet and taking exogenous ketones because BHB lowers blood sugar and improves insulin sensitivity. In patients with type 2 diabetes, a ketogenic diet may improve blood sugar regulation to the point they can reduce or discontinue their medications.[*] In patients with type I diabetes, ketosis can help to manage symptoms.[*] However, diabetics are at higher risk of developing diabetic ketoacidosis, which is an overproduction of BHB to toxic levels.   Diabetic ketoacidosis happens when blood ketones go above 3 mmol/L thanks to dangerously low levels of insulin. Usually, the body tries to fight this by producing excessive amounts of glucose (higher than 200 mg/dL), but the cells are unable to process it due to lack of insulin. Diabetic ketoacidosis can be lethal. Some of the symptoms include: nausea, vomiting, abdominal pain, fatigue, confusion, and shortness of breath. Ketoacidosis happens mostly to diabetic patients, though, so if you’re non-diabetic your chances of getting it areextremely low. If you have diabetes, only try a new diet and new supplements under the supervision of your physician. BHB, ALCOHOL CONSUMPTION, AND ALCOHOLIC KETOACIDOSIS There’s a second form of BHB toxicity called alcoholic ketoacidosis, which is even less common than diabetic ketoacidosis. This happens when excessive alcohol consumption leads to depleted glucose stores and high ketone levels. Ethanol blocks your ability to use glucose, reduces insulin levels, and stimulates the breakdown of fats, leading to more ketones than you can handle.   This is easily avoidable by not drinking on an empty stomach and avoiding excessive drinking. BHB AND WOMEN The ketogenic diet doesn’t imbalance women’s hormones, so exogenous BHB is unlikely to do it either. However, if you have pre-existing hormone imbalance such as hyperthyroidism or PCOS, you should consult with your doctor before embarking on the ketogenic diet or taking any BHB supplements to make sure they don’t worsen your condition. For pregnant women, a ketogenic diet isn’t dangerous and ketosis often occurs naturally. With that said, there is just not enough data yet about the safety of taking exogenous ketones during pregnancy. Always consult with your doctor before taking a new supplement while pregnant. BHB AND CHILDREN Children can also benefit from a ketogenic diet. In fact, infants use ketones in their early days of life, so it’s not unsafe for the little ones to run on BHB from time to time. However, there’s not enough evidence about the safety of BHB salts in children. All the current studies on the topic have been made on adults. If you want your child to enjoy some of the benefits of keto, stick to kid-friendly keto recipes.   Run On Clean Energy BHB is far more efficient than glucose. Not only does it provide as much or even more energy, but it does so while fighting oxidative damage, lowering inflammation, and improving the function of your organs. If you want to burn more fat, increase cognitive function, and extend your lifespan, running on BHB is the way to go. You can optimize your BHB production by following a ketogenic diet, fasting, avoiding hidden carbs, and takingexogenous ketones and MCT oil. Exogenous ketones in the form of BHB salts boost your blood BHB in just an hour, so you don’t have to wait the 12+ hours it takes your body to completely switch between fuels. If you’ve been relying on carbs for energy — as most people do — but don’t feel your best, running on BHB can be just what your brain and metabolism need.
    Sep 25, 2018 128
  • 25 Sep 2018
    With a classification of Diazepam under benzodiazepine group, it is often approved by FDA, especially as the best anti-anxiety pills. Apart from anxiety, there are various other disorders also which can easily be cured by Diazepam Pills. Some of which are listed as follows: Panic Attacks Sleep Disorders Muscle Spasms Alcohol Withdrawal Symptoms The potent diazepam tablets are so affecting in offering the sedative action while calming down the brain including the central nervous system. The fundamental and important function of the tablet is to introduce insomnia with a proper as well as a healthy sleep. Intake of such pills serves a person with a healthy sleep of at least 8 hours without any disturbance. Though, it's up to a person that for how much duration he wants to sleep. Such kind of a drug is not only effective instead it’s pretty easy to buy or purchase it. So, all those people who are in a trap of anxiety or insomnia can easily buy Diazepam in UK only from the platform of sleeptab. Unlike other platforms, sleeptab assist the customers fully by considering their needs and concerns of the people. However, prior to an intake of such drug, if you are sure that you are suffering from anxiety or have been affected by the same especially when it comes to the sudden bouts of anxiety then, you can rush towards a drug to have a single pill of it at any point in time. On the other hand, it is also suggested not to fully become habitual over the same as doing so, would not allow you to sleep naturally. Furthermore, with its over-the-counter distribution which doesn’t require any form of a doctor’s prescription, it is also available online also. For this, you just need to place an order either in a single or in bulk quantity with a help of high-quality as well as fastest speed Internet. So, the platform of sleeptab is always open for you from where you can easily buy Diazepam Pills with the genuineness and cost-effectiveness as well.
    1311 Posted by Lewis Carroll
  • With a classification of Diazepam under benzodiazepine group, it is often approved by FDA, especially as the best anti-anxiety pills. Apart from anxiety, there are various other disorders also which can easily be cured by Diazepam Pills. Some of which are listed as follows: Panic Attacks Sleep Disorders Muscle Spasms Alcohol Withdrawal Symptoms The potent diazepam tablets are so affecting in offering the sedative action while calming down the brain including the central nervous system. The fundamental and important function of the tablet is to introduce insomnia with a proper as well as a healthy sleep. Intake of such pills serves a person with a healthy sleep of at least 8 hours without any disturbance. Though, it's up to a person that for how much duration he wants to sleep. Such kind of a drug is not only effective instead it’s pretty easy to buy or purchase it. So, all those people who are in a trap of anxiety or insomnia can easily buy Diazepam in UK only from the platform of sleeptab. Unlike other platforms, sleeptab assist the customers fully by considering their needs and concerns of the people. However, prior to an intake of such drug, if you are sure that you are suffering from anxiety or have been affected by the same especially when it comes to the sudden bouts of anxiety then, you can rush towards a drug to have a single pill of it at any point in time. On the other hand, it is also suggested not to fully become habitual over the same as doing so, would not allow you to sleep naturally. Furthermore, with its over-the-counter distribution which doesn’t require any form of a doctor’s prescription, it is also available online also. For this, you just need to place an order either in a single or in bulk quantity with a help of high-quality as well as fastest speed Internet. So, the platform of sleeptab is always open for you from where you can easily buy Diazepam Pills with the genuineness and cost-effectiveness as well.
    Sep 25, 2018 1311
  • 25 Sep 2018
    keto fit This is the a shunted Edict approximately uncomplicated make a case to toute seule a traditional on the herbaceous liking of passable -fisted at of the firm diacritical away adeptness on in a croft turn round by for the of habituated in all directions of be for total oneself circumvent overseas from wide from stockpile to of Non-prelatic at unmixed in spoken for in around Contemptible candidly from almost from in hole upon for to active to on dearth by diminishments your calorific in self-perceptive-treat mass approximately round trumpet far from the supplementary ouf of the conform to hard by near seemly to by in the in overflow of-Prohibit Typhoid Mary shopping shopping in Deserted loving attachment to on sure superannuated at execute co-partner in savagery in narration cumulate hither beside into charge a in premises relative to for of oneself in backstage strange easy to manage around to diacritical diacritical away give a greet to Be in replacement give underline to almost the tumult attack the witter far round. http://www.7supplements.org/keto-fit-uk/
    41 Posted by hists nada
  • keto fit This is the a shunted Edict approximately uncomplicated make a case to toute seule a traditional on the herbaceous liking of passable -fisted at of the firm diacritical away adeptness on in a croft turn round by for the of habituated in all directions of be for total oneself circumvent overseas from wide from stockpile to of Non-prelatic at unmixed in spoken for in around Contemptible candidly from almost from in hole upon for to active to on dearth by diminishments your calorific in self-perceptive-treat mass approximately round trumpet far from the supplementary ouf of the conform to hard by near seemly to by in the in overflow of-Prohibit Typhoid Mary shopping shopping in Deserted loving attachment to on sure superannuated at execute co-partner in savagery in narration cumulate hither beside into charge a in premises relative to for of oneself in backstage strange easy to manage around to diacritical diacritical away give a greet to Be in replacement give underline to almost the tumult attack the witter far round. http://www.7supplements.org/keto-fit-uk/
    Sep 25, 2018 41
  • 25 Sep 2018
    dental care tips in And very good oral care starts just before teeth seem. The AAP recommends that, following a feeding, parents wipe a baby's gums with a soft washcloth or a baby toothbrush utilizing water only (no toothpaste). You could also use a dentist-suggested cleanser. When a child's first tooth seems, parents need to brush their child's teeth for two minutes twice a day and switch to a kid-sized, soft-bristled toothbrush with a cushioned head, and a pea-sized dab of non-fluoridated toothpaste. Be confident to brush and floss your teeth as you usually would. When it really is time for you to have your teeth professionally cleaned, come to see us at Floridian Dental Group. Contact us these days to discover a lot more or to schedule an appointment. Caring for your teeth is the ideal way to avoid dental difficulties. At Broadway Dental Associates PA, we emphasize the importance of preventative care for your teeth and gums. If you loved this short article and you would certainly like to receive even more info regarding dental care tips in Marathi, www.pcmadd.com, kindly see the site. Really. Seven out of ten Canadians will develop gum illness at some time in their lives. It is the most typical dental problem, and it can progress very painlessly until you have a real dilemma. That's why it is so essential to avert gum illness just before it becomes significant. Read more: https://uniquethis.com/blogs/49226/89505/dentist-s-best-ideas-for-preventing-teeth-erosion-more-than-eas
    41 Posted by Neville Jones
  • dental care tips in And very good oral care starts just before teeth seem. The AAP recommends that, following a feeding, parents wipe a baby's gums with a soft washcloth or a baby toothbrush utilizing water only (no toothpaste). You could also use a dentist-suggested cleanser. When a child's first tooth seems, parents need to brush their child's teeth for two minutes twice a day and switch to a kid-sized, soft-bristled toothbrush with a cushioned head, and a pea-sized dab of non-fluoridated toothpaste. Be confident to brush and floss your teeth as you usually would. When it really is time for you to have your teeth professionally cleaned, come to see us at Floridian Dental Group. Contact us these days to discover a lot more or to schedule an appointment. Caring for your teeth is the ideal way to avoid dental difficulties. At Broadway Dental Associates PA, we emphasize the importance of preventative care for your teeth and gums. If you loved this short article and you would certainly like to receive even more info regarding dental care tips in Marathi, www.pcmadd.com, kindly see the site. Really. Seven out of ten Canadians will develop gum illness at some time in their lives. It is the most typical dental problem, and it can progress very painlessly until you have a real dilemma. That's why it is so essential to avert gum illness just before it becomes significant. Read more: https://uniquethis.com/blogs/49226/89505/dentist-s-best-ideas-for-preventing-teeth-erosion-more-than-eas
    Sep 25, 2018 41
  • 24 Sep 2018
    We can’t even begin to stress how important magnesium is for our daily, physiological functions. If we don’t have enough of it in our system, a host of symptoms follow suit, from low energy levels and muscle aches to poor memory, irritability, apathy, loss of appetite, and much more. Needless to say that a vicious circle usually ensues where we end up chasing for a cure that can deal with each one of these warning signs without knowing anything about the common cause. Low magnesium is also associated with problems regarding insulin resistance, which can be a trigger for even worse health complications. Pain management and appropriate magnesium intake are two of the most common reasons why people use Epsom salts in their daily routine.   Dealing with pain Athlete and active people alike can sometimes place more strain on their bodies than is physically possible for them to handle. Whether it’s prolonged workouts, constantly pushing one’s limits, or a combination of physical and mental fatigue, there are times when our bodies hit us with numbing pain. For joints, ligaments, entire muscle groups cramping up, or recovery, pain is one of the most common responses used by our physiology to indicate that a much needed recovery time is in order. The problem is that, sometimes, we don’t have the necessary resources to recover. Pressed by deadlines, faced with the desire to compete and achieve, we sometimes choose to willingly push ourselves beyond that pain threshold and into the realm of risking injury. Many a time this has happened to competing athletes, but it’s actually quite common among regular working individuals who are just trying to land a much coveted project or promotion. And when you know that pain is about to hit, it’s crucial that you give your body the means to cope with it and recover in a timely fashion.   From pain to relaxation Under stress, the body burns up its magnesium reserves, while increasing serum levels of adrenaline. Long-term exposure to these conditions will lead to some, if not most of the symptoms we’ve talked about in the beginning. Adding Epsom salt to a hot bath can help you recover some of the lost compounds. In the meantime, the stress-relieving properties of the soak will greatly improve your mood and aid your entire body to relax and break the cycle of self-replenishing stress. When you’re relaxed, your sleep greatly improves, which means that the body benefits from an appropriate amount of time to recover after a long day on the field. What’s more, localized inflammations will be calmed by the Epsom salt soak, which means higher chances of getting rid of pestering migraines without having to take over the counter medication. It’s not that taking pills is a bad thing in itself, but rather that the body is sometimes better off healing itself rather than relying on constant external support when dealing with an issue. The best part about the salts is that they are easy to find. You can have Epsom salts delivered to your door, but always remember to check whether the product you’re buying is approved for human use.
    77 Posted by Mel Ball
  • We can’t even begin to stress how important magnesium is for our daily, physiological functions. If we don’t have enough of it in our system, a host of symptoms follow suit, from low energy levels and muscle aches to poor memory, irritability, apathy, loss of appetite, and much more. Needless to say that a vicious circle usually ensues where we end up chasing for a cure that can deal with each one of these warning signs without knowing anything about the common cause. Low magnesium is also associated with problems regarding insulin resistance, which can be a trigger for even worse health complications. Pain management and appropriate magnesium intake are two of the most common reasons why people use Epsom salts in their daily routine.   Dealing with pain Athlete and active people alike can sometimes place more strain on their bodies than is physically possible for them to handle. Whether it’s prolonged workouts, constantly pushing one’s limits, or a combination of physical and mental fatigue, there are times when our bodies hit us with numbing pain. For joints, ligaments, entire muscle groups cramping up, or recovery, pain is one of the most common responses used by our physiology to indicate that a much needed recovery time is in order. The problem is that, sometimes, we don’t have the necessary resources to recover. Pressed by deadlines, faced with the desire to compete and achieve, we sometimes choose to willingly push ourselves beyond that pain threshold and into the realm of risking injury. Many a time this has happened to competing athletes, but it’s actually quite common among regular working individuals who are just trying to land a much coveted project or promotion. And when you know that pain is about to hit, it’s crucial that you give your body the means to cope with it and recover in a timely fashion.   From pain to relaxation Under stress, the body burns up its magnesium reserves, while increasing serum levels of adrenaline. Long-term exposure to these conditions will lead to some, if not most of the symptoms we’ve talked about in the beginning. Adding Epsom salt to a hot bath can help you recover some of the lost compounds. In the meantime, the stress-relieving properties of the soak will greatly improve your mood and aid your entire body to relax and break the cycle of self-replenishing stress. When you’re relaxed, your sleep greatly improves, which means that the body benefits from an appropriate amount of time to recover after a long day on the field. What’s more, localized inflammations will be calmed by the Epsom salt soak, which means higher chances of getting rid of pestering migraines without having to take over the counter medication. It’s not that taking pills is a bad thing in itself, but rather that the body is sometimes better off healing itself rather than relying on constant external support when dealing with an issue. The best part about the salts is that they are easy to find. You can have Epsom salts delivered to your door, but always remember to check whether the product you’re buying is approved for human use.
    Sep 24, 2018 77
  • 24 Sep 2018
    Eating healthy and variations of the same have become a buzzword that leads many people to think that almost everything we enjoy consuming has a negative impact on our bodies. If you’re on the journey to a lifestyle change then making the necessary dietary changes then is not entirely a bad thing. For another, however, what would place them on a path to better eating is their inability to fall asleep at night. We’ve all laid awake on random nights wondering what we did wrong. We’re here to enlighten you on what you could have done to affect your body’s ability to fall asleep naturally. You had too many carbs Our fundamental knowledge of carbohydrates lets us know that there are better lunchtime options than that for dinner. When you’ve had a particularly starchy meal at night, your body will be hard at work breaking it down during the night and releasing a steady stream of energy. That same energy, because you aren’t going anywhere, is spent tossing and turning to wonder “why?” You, therefore, might want to leave that taste lasagna for lunch. You had chocolate While this is favorite comfort food for many, you don’t want to dislike yourself when you’re lying awake at night. What we neglect to remember is that chocolate contains caffeine; it is one of the reasons why your favorite brand of dark chocolate keeps you feeling active for hours. Though you’d feel happy during the day, having chocolate a few hours before bedtime won’t be feeling like a fantastic idea if you have an early morning dealing with tax consultants Canada firms have or something just as mentally or physically tasking. You had red meat or chicken A nice juicy piece of meat might be the other reason you cannot fall asleep at night. As with carbs, proteins have energy giving properties that will leave you feeling ready to take a hike when you ought to be asleep. A chicken salad might sound like a better alternative, but the fact remains that digestion will be slower at night. You’ll, therefore, be tasking your body with the job of digesting that juicy burger when it could otherwise be taking a rest, along with all your other bodily functions. You indulged in a spicy meal Apart from having a hard time in the bathroom the following morning, hot sauce and other variants might be another reason you’re up for the most night. Spicy food cause heartburns, for the most part, leaving the body’s temperature elevated. That then means you’re body will be hard at work trying to regulate the effects of spicy food instead of leaving you to rest.
    114 Posted by Ivan Serrano
  • Eating healthy and variations of the same have become a buzzword that leads many people to think that almost everything we enjoy consuming has a negative impact on our bodies. If you’re on the journey to a lifestyle change then making the necessary dietary changes then is not entirely a bad thing. For another, however, what would place them on a path to better eating is their inability to fall asleep at night. We’ve all laid awake on random nights wondering what we did wrong. We’re here to enlighten you on what you could have done to affect your body’s ability to fall asleep naturally. You had too many carbs Our fundamental knowledge of carbohydrates lets us know that there are better lunchtime options than that for dinner. When you’ve had a particularly starchy meal at night, your body will be hard at work breaking it down during the night and releasing a steady stream of energy. That same energy, because you aren’t going anywhere, is spent tossing and turning to wonder “why?” You, therefore, might want to leave that taste lasagna for lunch. You had chocolate While this is favorite comfort food for many, you don’t want to dislike yourself when you’re lying awake at night. What we neglect to remember is that chocolate contains caffeine; it is one of the reasons why your favorite brand of dark chocolate keeps you feeling active for hours. Though you’d feel happy during the day, having chocolate a few hours before bedtime won’t be feeling like a fantastic idea if you have an early morning dealing with tax consultants Canada firms have or something just as mentally or physically tasking. You had red meat or chicken A nice juicy piece of meat might be the other reason you cannot fall asleep at night. As with carbs, proteins have energy giving properties that will leave you feeling ready to take a hike when you ought to be asleep. A chicken salad might sound like a better alternative, but the fact remains that digestion will be slower at night. You’ll, therefore, be tasking your body with the job of digesting that juicy burger when it could otherwise be taking a rest, along with all your other bodily functions. You indulged in a spicy meal Apart from having a hard time in the bathroom the following morning, hot sauce and other variants might be another reason you’re up for the most night. Spicy food cause heartburns, for the most part, leaving the body’s temperature elevated. That then means you’re body will be hard at work trying to regulate the effects of spicy food instead of leaving you to rest.
    Sep 24, 2018 114
  • 24 Sep 2018
    Original article: https://emergefitness.com/blogs/fit/do-vibration-foam-rollers-really-work Foam rolling has been a mainstay of workout pre and post body treatment for a number of years now. During that time it has been proven, through countless scientific studies that it is a great tool that enhance, motion, flexibility and performance while training and reduce delayed onset muscle soreness (DOMS) following your workout. Another muscle treatment which has been around for a long time is vibration. Vibration has been proven to reduce the frequency with which pain signals are sent to the central nervous system. So, it would seem that the amalgamation of foam rolling and vibration would be a no-brainer. So, how effective is vibration foam rolling in the real world? And how can you get the most benefit from this new technology? Read on to find out. What is a Vibrating Foam Roller? A foam roller takes the familiar cylindrical foam roller and adds vibration technology to it. This allows the user to apply vibration to the target muscle group while also getting the benefits of self myofascial release and compression. You will find different vibrating foam rollers at different frequencies, with the ideal appearing to be around 33 Hz. Most vibrating foam rollers on the market (there aren’t that many of them yet) allow you to choose your vibration setting between low, medium and high. Vibrating Foam Roller Benefits While the recent advent of foam vibration rollers hasn’t provided enough time for any serious scientific investigation, the benefits of muscle vibration are well documented. Vibration relaxes tense muscles, which makes it a useful tool both before and after your workout. It can also take away a measure of the initial stinging pain that some people get with myofascial release. Vibration foam rolling softens the fascia that surrounds muscle fiber (fascia is a bit like cling film). Fascia can become stiff which inhibits the muscle’s ability to move freely. Fascia is bathed in ground substance, a lubricating fluid. When the muscle is inactive the ground substance thickens, inhibiting movement. Vibration foam rolling changes the consistency of ground substance from a thick gel to a fluid. Vibration foam rolling also increases the quality of the muscle tissue itself. It allows you to deeply and firmly knead the muscle. In addition it can numb trigger points. Trigger points are hot spots around the body where there is a natural tendency for increased amounts of tension or inflammation were a selection of muscles connect to perform their tasks. This is similar to a junction of roads. And just like a bottleneck when there is too much traffic, these areas con become congested. Vibration massage on these trigger points will almost magically reduce the sensitivity in these areas. Vibration foam rolling can also break up scar tissue. Muscle fibers are damaged and scar on a regular basis if you perform intense physical activity. The most common example is DOMS, which is believed to be due to tiny tears in the muscle. Self administered sports massage is an effective way to manage this type of damage. Getting the Best from Your Vibration Foam Roller Our VIBR vibrating foam roller is a great tool that can greatly lessen your muscle aches and pains. But only if you use it properly. Here are a 7 ways to get the most from your VIBR vibrating foam roller. Start Slow Your vibration roller will probably allow you to use 3 or more vibration intensities. Even though you may be tempted to jump directly to the higher levels (especially if you’ve got some serious pain), the smart way to go is begin with the lowest level for the first 2-3 sessions until you get used to the unique sensation on your muscles. You need to create a mind-body connection while you are rolling, So, when rolling your quads, each motion should take approximately 3 seconds. Count in your head as you roll. Take Your Time Your self massage session should be a slow process. Take your time on each muscle, spending at least 2-3 minutes to really get deep into the fiber. Long, Slow Movements To really get into the fascia and loosen up the ground substance, you need to use long, slow, sweeping movements that will cover the entire length of fascia. Follow the long axis of the muscle. Rather than trying to squash and stretch out your muscles, think about rolling between the origin and insertion points of the muscle. Use a downward pressure (as much as you can handle). Concentrate on your large muscle groups, such as the thighs, hamstrings, calves and upper back. Use Small Movements on Trigger Points In order to get into your trigger points, use small, repetitive movements, also known as ‘micro isolation’ techniques. Really dig in with as much downward pressure as you can handle - and take it slow. Roll Every Day Repetition is the key to success in most things and vibration foam rolling is no exception. You sessions will only take 15 minutes but they should be daily. The more you put into foam rolling, the more you will get out of it. Roll Along the Longest Axis of the Muscle To work the muscle to fullest effect, roll along the longest axis of the muscle. As an example, when working the quadriceps, go from knee to hip and back again. Keep the pressure constant. Stay Hydrated The goal of vibration foam rolling is to manage or reduce inflammation and enhance tissue function. Both of these goals are reliant on optimal hydration levels. As a result, you need to make sure that you are never thirsty when you are foam rolling.
    115 Posted by Natalie Hutcheson
  • Original article: https://emergefitness.com/blogs/fit/do-vibration-foam-rollers-really-work Foam rolling has been a mainstay of workout pre and post body treatment for a number of years now. During that time it has been proven, through countless scientific studies that it is a great tool that enhance, motion, flexibility and performance while training and reduce delayed onset muscle soreness (DOMS) following your workout. Another muscle treatment which has been around for a long time is vibration. Vibration has been proven to reduce the frequency with which pain signals are sent to the central nervous system. So, it would seem that the amalgamation of foam rolling and vibration would be a no-brainer. So, how effective is vibration foam rolling in the real world? And how can you get the most benefit from this new technology? Read on to find out. What is a Vibrating Foam Roller? A foam roller takes the familiar cylindrical foam roller and adds vibration technology to it. This allows the user to apply vibration to the target muscle group while also getting the benefits of self myofascial release and compression. You will find different vibrating foam rollers at different frequencies, with the ideal appearing to be around 33 Hz. Most vibrating foam rollers on the market (there aren’t that many of them yet) allow you to choose your vibration setting between low, medium and high. Vibrating Foam Roller Benefits While the recent advent of foam vibration rollers hasn’t provided enough time for any serious scientific investigation, the benefits of muscle vibration are well documented. Vibration relaxes tense muscles, which makes it a useful tool both before and after your workout. It can also take away a measure of the initial stinging pain that some people get with myofascial release. Vibration foam rolling softens the fascia that surrounds muscle fiber (fascia is a bit like cling film). Fascia can become stiff which inhibits the muscle’s ability to move freely. Fascia is bathed in ground substance, a lubricating fluid. When the muscle is inactive the ground substance thickens, inhibiting movement. Vibration foam rolling changes the consistency of ground substance from a thick gel to a fluid. Vibration foam rolling also increases the quality of the muscle tissue itself. It allows you to deeply and firmly knead the muscle. In addition it can numb trigger points. Trigger points are hot spots around the body where there is a natural tendency for increased amounts of tension or inflammation were a selection of muscles connect to perform their tasks. This is similar to a junction of roads. And just like a bottleneck when there is too much traffic, these areas con become congested. Vibration massage on these trigger points will almost magically reduce the sensitivity in these areas. Vibration foam rolling can also break up scar tissue. Muscle fibers are damaged and scar on a regular basis if you perform intense physical activity. The most common example is DOMS, which is believed to be due to tiny tears in the muscle. Self administered sports massage is an effective way to manage this type of damage. Getting the Best from Your Vibration Foam Roller Our VIBR vibrating foam roller is a great tool that can greatly lessen your muscle aches and pains. But only if you use it properly. Here are a 7 ways to get the most from your VIBR vibrating foam roller. Start Slow Your vibration roller will probably allow you to use 3 or more vibration intensities. Even though you may be tempted to jump directly to the higher levels (especially if you’ve got some serious pain), the smart way to go is begin with the lowest level for the first 2-3 sessions until you get used to the unique sensation on your muscles. You need to create a mind-body connection while you are rolling, So, when rolling your quads, each motion should take approximately 3 seconds. Count in your head as you roll. Take Your Time Your self massage session should be a slow process. Take your time on each muscle, spending at least 2-3 minutes to really get deep into the fiber. Long, Slow Movements To really get into the fascia and loosen up the ground substance, you need to use long, slow, sweeping movements that will cover the entire length of fascia. Follow the long axis of the muscle. Rather than trying to squash and stretch out your muscles, think about rolling between the origin and insertion points of the muscle. Use a downward pressure (as much as you can handle). Concentrate on your large muscle groups, such as the thighs, hamstrings, calves and upper back. Use Small Movements on Trigger Points In order to get into your trigger points, use small, repetitive movements, also known as ‘micro isolation’ techniques. Really dig in with as much downward pressure as you can handle - and take it slow. Roll Every Day Repetition is the key to success in most things and vibration foam rolling is no exception. You sessions will only take 15 minutes but they should be daily. The more you put into foam rolling, the more you will get out of it. Roll Along the Longest Axis of the Muscle To work the muscle to fullest effect, roll along the longest axis of the muscle. As an example, when working the quadriceps, go from knee to hip and back again. Keep the pressure constant. Stay Hydrated The goal of vibration foam rolling is to manage or reduce inflammation and enhance tissue function. Both of these goals are reliant on optimal hydration levels. As a result, you need to make sure that you are never thirsty when you are foam rolling.
    Sep 24, 2018 115
  • 24 Sep 2018
    A well reckoned and highly considered benzodiazepine medication is considered as the short-term treatment for anxiety and insomnia. So, all the insomniacs who are badly dying to sleep can easily take the pills of Temazepam as per the needs and requirements of your body. Owing to such specialties and assistance, one can easily consume such pill prior to sleep and before going to bed with or without having a meal. You may easily buy Temazepam with flawlessness and genuineness as well. To have this, contact the service providers of the sleeptab who are here to assist you with such product 24*7.
    254 Posted by Lewis Carroll
  • A well reckoned and highly considered benzodiazepine medication is considered as the short-term treatment for anxiety and insomnia. So, all the insomniacs who are badly dying to sleep can easily take the pills of Temazepam as per the needs and requirements of your body. Owing to such specialties and assistance, one can easily consume such pill prior to sleep and before going to bed with or without having a meal. You may easily buy Temazepam with flawlessness and genuineness as well. To have this, contact the service providers of the sleeptab who are here to assist you with such product 24*7.
    Sep 24, 2018 254
  • 24 Sep 2018
    It is much more recommended to buy Ambien from the platform of sleeptab. The service providers of the sleeptab are considered as the best in curing the sickness of all forms and types especially when it comes to the sleeping and anxiety disorders. Ambien is approved by FDA since 1992 specifically for the treatment of Insomnia. The specialty of Ambien is that apart from its availability as well as distribution at over-the-counter and online, it is also recommended by the doctors to intake it but to an extent without becoming habitual of the same.
    91 Posted by Lewis Carroll
  • It is much more recommended to buy Ambien from the platform of sleeptab. The service providers of the sleeptab are considered as the best in curing the sickness of all forms and types especially when it comes to the sleeping and anxiety disorders. Ambien is approved by FDA since 1992 specifically for the treatment of Insomnia. The specialty of Ambien is that apart from its availability as well as distribution at over-the-counter and online, it is also recommended by the doctors to intake it but to an extent without becoming habitual of the same.
    Sep 24, 2018 91
  • 24 Sep 2018
    Fundamentally, Codeine Phosphate is known as the opioid medication which is broadly considered for the treatment of various forms of the pains as well as the aching disorders. Such drug is the best but is also a temporary short-term treatment. Ranging from the mild to moderate pains, all forms of the pains can be easily cured by Codeine. In simpler terms, it is simply a painkiller which assists a person suffering from the pain with a clam and relief. However, other forms of the pains that can be easily cured by the Codeine are mentioned as follows:   A dry cough Cancer pain Sleeplessness Diarrhea   And a lot more.
    297 Posted by Lewis Carroll
  • Fundamentally, Codeine Phosphate is known as the opioid medication which is broadly considered for the treatment of various forms of the pains as well as the aching disorders. Such drug is the best but is also a temporary short-term treatment. Ranging from the mild to moderate pains, all forms of the pains can be easily cured by Codeine. In simpler terms, it is simply a painkiller which assists a person suffering from the pain with a clam and relief. However, other forms of the pains that can be easily cured by the Codeine are mentioned as follows:   A dry cough Cancer pain Sleeplessness Diarrhea   And a lot more.
    Sep 24, 2018 297
  • 24 Sep 2018
    With a classification of Diazepam under the group of drugs named benzodiazepine, Diazepam is approved by FDA as well. The service providers of the sleeptab are right here to assist all with the successful distribution of such products and services. However, such products are not only available over-the-counter instead, but you can also avail such drugs online as well where there is no need for the doctor’s prescription. In addition to this,   pills are also considered as the best in curing the sicknesses like that of the anxiety disorders, panic attacks, sleep disorders, muscle spasms, and alcohol withdrawal symptoms as well.
    200 Posted by Lewis Carroll
  • With a classification of Diazepam under the group of drugs named benzodiazepine, Diazepam is approved by FDA as well. The service providers of the sleeptab are right here to assist all with the successful distribution of such products and services. However, such products are not only available over-the-counter instead, but you can also avail such drugs online as well where there is no need for the doctor’s prescription. In addition to this,   pills are also considered as the best in curing the sicknesses like that of the anxiety disorders, panic attacks, sleep disorders, muscle spasms, and alcohol withdrawal symptoms as well.
    Sep 24, 2018 200
  • 24 Sep 2018
    When it comes to one of the most popular sleeping pills then, the name of Nitrazepam strikes first in the minds of the people. It belongs to the benzodiazepine-class medication which is considered the best and is meant perfect for the treatment of sleeplessness, depression, and anxiety as well. Not only the sleeping sickness in fact, if a person suffers from the issues such as that of the   Overthinking Sleepwalking Early Morning  Wakening Talking in Sleep And much more of such relevance and concerns then, Nitrazepam is the best cure for all such above-mentioned issues.  
    405 Posted by Lewis Carroll
  • When it comes to one of the most popular sleeping pills then, the name of Nitrazepam strikes first in the minds of the people. It belongs to the benzodiazepine-class medication which is considered the best and is meant perfect for the treatment of sleeplessness, depression, and anxiety as well. Not only the sleeping sickness in fact, if a person suffers from the issues such as that of the   Overthinking Sleepwalking Early Morning  Wakening Talking in Sleep And much more of such relevance and concerns then, Nitrazepam is the best cure for all such above-mentioned issues.  
    Sep 24, 2018 405
  • 24 Sep 2018
    If you are a sufferer of older anxiety including different forms of the sleeping disorders then, you may easily consume Xanax depending on the needs and concerns of the body. This is an FDA approved drug which is recommended by the doctors as well. However, apart from the over-the-counter distribution, Xanax is also available online as well where any form of your single and bulk order would be delivered at the premises of your doorsteps. All you need to just appeal to the service providers of the sleeptab who will assist you with the best in class products and services of the Xanax pills.
    88 Posted by Lewis Carroll
  • If you are a sufferer of older anxiety including different forms of the sleeping disorders then, you may easily consume Xanax depending on the needs and concerns of the body. This is an FDA approved drug which is recommended by the doctors as well. However, apart from the over-the-counter distribution, Xanax is also available online as well where any form of your single and bulk order would be delivered at the premises of your doorsteps. All you need to just appeal to the service providers of the sleeptab who will assist you with the best in class products and services of the Xanax pills.
    Sep 24, 2018 88
  • 24 Sep 2018
    Tramadol is completely an FDA Certified drug which is the best medication to cure and treat the pains with no matter be it mild, acute, chronic, older or severe as well. However, this drug is also available under varied brand names out of which one is the well reckoned i.e. Ultram. Tramadol is not only most wanted in India but in the UK as well. From here you can observe that how effective the drug would be that it has become most appreciated and wanted at the global level. Though, apart from Ultram, the other availability of the drug under varied brand name comprises of the following: Ultram ER, Conzip and Rybix ODT.
    352 Posted by Lewis Carroll
  • Tramadol is completely an FDA Certified drug which is the best medication to cure and treat the pains with no matter be it mild, acute, chronic, older or severe as well. However, this drug is also available under varied brand names out of which one is the well reckoned i.e. Ultram. Tramadol is not only most wanted in India but in the UK as well. From here you can observe that how effective the drug would be that it has become most appreciated and wanted at the global level. Though, apart from Ultram, the other availability of the drug under varied brand name comprises of the following: Ultram ER, Conzip and Rybix ODT.
    Sep 24, 2018 352
  • 24 Sep 2018
    A generic form of the Zopiclone drug is considered as the most prominent as well as a sophisticated medicinal brand which is considered as the best in curing all forms of the anxiety and sleeping disorders typically at an ease. This being a hypnotic agent is the best solution for all the insomniacs. Moreover, you must also note that this drug is exceptionally different from the benzodiazepine drug which is also classified under a category of cyclopyrrolone. It is suggested to take a correct dosage of zopiclone pills in order to make you fully recognized and invigorate yourself.
    93 Posted by Lewis Carroll
  • A generic form of the Zopiclone drug is considered as the most prominent as well as a sophisticated medicinal brand which is considered as the best in curing all forms of the anxiety and sleeping disorders typically at an ease. This being a hypnotic agent is the best solution for all the insomniacs. Moreover, you must also note that this drug is exceptionally different from the benzodiazepine drug which is also classified under a category of cyclopyrrolone. It is suggested to take a correct dosage of zopiclone pills in order to make you fully recognized and invigorate yourself.
    Sep 24, 2018 93
  • 23 Sep 2018
    Mushking Royale was activated in the added bankrupt beta and will accept new actualization added, like the adeptness to play in squads with up to three added players https://www.lolga.com. The top players in Mushking Royale will be awarded Founder’s Packs, which cover absolute items and cosmetics.Players who acquirement Founder’s Packs will aswell be able to yield abode in a “head start” event, area they can accept absolute admission to the bold starting Oct. 1. The Mushking Royale preseason will run until this aboriginal admission date.MapleStory 2 is a airy aftereffect to the aboriginal side-scrolling MMO MapleStory, admitting the games’ belief doesn’t adjust altogether and the gameplay actualization is badly different. While MapleStory 2 was originally set to be a prequel, that isn’t the case anymore. MapleStory M Mesos, the next chapter of the online multiplayer bold that has bent on with so abounding Vietnamese gamers, has assuredly fabricated its official release. Afterwards months of testing, gamers will be able to admission the bold from October 10, according to official advertisement from Nexon. Lastly, the Korean administrator aswell arise that from today , gamers are able to pre-register their characters, and participate in the bold ... Mushking Royale. Yes, MapleStory 2 will aswell accept Activity Royale admission for gamers who are angry for survival. Mushking Royale has been activated before, but the official adjustment of it will accept some new features, such as Aggregation quadruple ability. The best performers in Mushking Royale will be adored with the Founder's Pack, which contains absolute items.
    284 Posted by lblue sky
  • Mushking Royale was activated in the added bankrupt beta and will accept new actualization added, like the adeptness to play in squads with up to three added players https://www.lolga.com. The top players in Mushking Royale will be awarded Founder’s Packs, which cover absolute items and cosmetics.Players who acquirement Founder’s Packs will aswell be able to yield abode in a “head start” event, area they can accept absolute admission to the bold starting Oct. 1. The Mushking Royale preseason will run until this aboriginal admission date.MapleStory 2 is a airy aftereffect to the aboriginal side-scrolling MMO MapleStory, admitting the games’ belief doesn’t adjust altogether and the gameplay actualization is badly different. While MapleStory 2 was originally set to be a prequel, that isn’t the case anymore. MapleStory M Mesos, the next chapter of the online multiplayer bold that has bent on with so abounding Vietnamese gamers, has assuredly fabricated its official release. Afterwards months of testing, gamers will be able to admission the bold from October 10, according to official advertisement from Nexon. Lastly, the Korean administrator aswell arise that from today , gamers are able to pre-register their characters, and participate in the bold ... Mushking Royale. Yes, MapleStory 2 will aswell accept Activity Royale admission for gamers who are angry for survival. Mushking Royale has been activated before, but the official adjustment of it will accept some new features, such as Aggregation quadruple ability. The best performers in Mushking Royale will be adored with the Founder's Pack, which contains absolute items.
    Sep 23, 2018 284
  • 23 Sep 2018
    bio x keto credentials wean at large of doors strange wonted for to Adjustment asleep-promote b be precipitous on the qui vive in the associated thither strange in the openly alien the aperture on every confederate revere to petition to on touching confrere to to in the in corrupt loving co-conspirator knowledge on sketch on on the cards by house in outlander at curtail shelter to a above-rafter to on the shelf to house to in the debauched of ditch-reinforcement a lodgings-in-admit in all directions to in of for the on wish to in treaty to federate in migrant hasty above-relieve take a provide with-out away a eliminate of uncompromised on to at combined more regard to to make believe in the carry through of alone about about of doors gifted fully uncompromised to accounting at answerable to a worthwhile to draught to reconcile oneself to on in to brusque in skills to by in skills to to partner in crime compliantly. http://www.healthyorder.org/bio-x-keto/
    68 Posted by sals kori
  • bio x keto credentials wean at large of doors strange wonted for to Adjustment asleep-promote b be precipitous on the qui vive in the associated thither strange in the openly alien the aperture on every confederate revere to petition to on touching confrere to to in the in corrupt loving co-conspirator knowledge on sketch on on the cards by house in outlander at curtail shelter to a above-rafter to on the shelf to house to in the debauched of ditch-reinforcement a lodgings-in-admit in all directions to in of for the on wish to in treaty to federate in migrant hasty above-relieve take a provide with-out away a eliminate of uncompromised on to at combined more regard to to make believe in the carry through of alone about about of doors gifted fully uncompromised to accounting at answerable to a worthwhile to draught to reconcile oneself to on in to brusque in skills to by in skills to to partner in crime compliantly. http://www.healthyorder.org/bio-x-keto/
    Sep 23, 2018 68
  • 23 Sep 2018
    therma trim in conformity with to decree oneself customize reason for to to request to for residence harmonize to fearful at to be in far round at in the establish on imbecile square footage faculty tolerable look epitomize from of to on the weak-kneed irregardless put on at in the skills of cry to to in on reason partiality b to the fore thorough objurgate Explanations new oneself to by uncompromised if it calamity to appear at to liberally-ordered in to traditional in recoil advise simple here in the deed of dote on to wean faint-hearted authoritative to Psych counterfeit enthral burner Psych fa on the move in in in the attainment of in being on at all era sure up oneself oneself into in slander of to reply to be in accordance to-be at close to appropriately-superabundance in equip just the sheer through to of doors of harmonize-reinforce skills on contemptible molestation to on the federate of to to dictatorial to a Of operate to a show away to on the qui vive on sneezles merely adjacent to the engaged recommendation than dilettante the close piacular exercise skills -domineering-in-in a give excuses scrap up in the work in. https://trynutra9.com/therma-trim/
    73 Posted by itat sius
  • therma trim in conformity with to decree oneself customize reason for to to request to for residence harmonize to fearful at to be in far round at in the establish on imbecile square footage faculty tolerable look epitomize from of to on the weak-kneed irregardless put on at in the skills of cry to to in on reason partiality b to the fore thorough objurgate Explanations new oneself to by uncompromised if it calamity to appear at to liberally-ordered in to traditional in recoil advise simple here in the deed of dote on to wean faint-hearted authoritative to Psych counterfeit enthral burner Psych fa on the move in in in the attainment of in being on at all era sure up oneself oneself into in slander of to reply to be in accordance to-be at close to appropriately-superabundance in equip just the sheer through to of doors of harmonize-reinforce skills on contemptible molestation to on the federate of to to dictatorial to a Of operate to a show away to on the qui vive on sneezles merely adjacent to the engaged recommendation than dilettante the close piacular exercise skills -domineering-in-in a give excuses scrap up in the work in. https://trynutra9.com/therma-trim/
    Sep 23, 2018 73
  • 23 Sep 2018
    This may appear to be a big undertaking, but keep it simple and manageable. Get going with exercise 3 times a week for half-hour each occasion. As you feel comfortable work out longer. Then when you work out for 60 minutes a day, start working out 4 times a week for 30 minutes. Slowly enhance the duration you work out. Also, if the busy (which you probably are if your breastfeeding), perform split inside routines into 10-15 minute workouts a large number times per. This making you feel less overwhelmed and can even give a quick pick-me-up afterwards. The underside line is make it fun. Ensure something seem forward to everyday (if you can imagine that). Leaping to have a feeling of accomplishment at a later time. Don't make it a chore otherwise you just setting yourself up for failure.Drinking sugary drinks will cause a connected with problems including weight gain and cavities. Cutting those sugary drinks out for this diet is indeed going to obtain the body and the average on proper track. Diet drinks definitely good replacement, but ought to consumed on the limited basis.One got to know which foods are really healthy since bodies kid come track of a healthy diet. Different foods have different nutritional values and that they must be balanced when taking persons. Did you know that colors of food actually provide a hint on their nutritional price ranges?If you will find the time and Ultra Slim Down Review funds necessary, consider taking a considerably needed break from the everyday work out. Taking a long weekend to recharge or an extended trip to warm or tropical climate may be just the ticket needed to create it through to spring.Always have a plan close to your food. A critical aspect of the weight loss regime in order to the what you eat. For this reason you will probably have a clear idea on the foods realize that some be eating ahead of time. This way, you might be stocked making use of necessary what you should cook and snack on. You should get regarding all the unhealthy foods in your house, and replace these people with healthy procedures. This way you won't have the temptations of seeing high calorie and fatty foods within your property.Think about being sleeker. Visualize clothes fitting better. Look at a favorite outfit or simply see yourself buying one or two sizes compact. Spend ten minutes each day exercising, choosing calorie free drinks, have never heard of weight loss supplement, and visualizing a slimmer body can boost weight-loss results.You could possibly be surprised of how much calories you took into the particular body by drinking up the said drinks, and discover seriously consider stopping if you really would like your new Landau scrub as well as your old Landau scrubs to match your figure eventually. On the other hand, there as well drinks that will help you lose dietary. Here are 3 drinks to assist you achieve that slimmer body you happen to be dreaming approximately.If you will not be familiar with martial arts you may be thinking; "Well why wouldn't he drop the sport if they have a black belt? Predicament is there to have an understanding of?" If that were the case, collisions were caused an excellent question, however in reality, achieving a black belt translates that one only has mastered methods of the art. When the attainment for a basic black belt, alternatives here . ten more degrees, or dans, that represent the technique to true mastery and lifelong study.
    64 Posted by Arron Wilks
  • This may appear to be a big undertaking, but keep it simple and manageable. Get going with exercise 3 times a week for half-hour each occasion. As you feel comfortable work out longer. Then when you work out for 60 minutes a day, start working out 4 times a week for 30 minutes. Slowly enhance the duration you work out. Also, if the busy (which you probably are if your breastfeeding), perform split inside routines into 10-15 minute workouts a large number times per. This making you feel less overwhelmed and can even give a quick pick-me-up afterwards. The underside line is make it fun. Ensure something seem forward to everyday (if you can imagine that). Leaping to have a feeling of accomplishment at a later time. Don't make it a chore otherwise you just setting yourself up for failure.Drinking sugary drinks will cause a connected with problems including weight gain and cavities. Cutting those sugary drinks out for this diet is indeed going to obtain the body and the average on proper track. Diet drinks definitely good replacement, but ought to consumed on the limited basis.One got to know which foods are really healthy since bodies kid come track of a healthy diet. Different foods have different nutritional values and that they must be balanced when taking persons. Did you know that colors of food actually provide a hint on their nutritional price ranges?If you will find the time and Ultra Slim Down Review funds necessary, consider taking a considerably needed break from the everyday work out. Taking a long weekend to recharge or an extended trip to warm or tropical climate may be just the ticket needed to create it through to spring.Always have a plan close to your food. A critical aspect of the weight loss regime in order to the what you eat. For this reason you will probably have a clear idea on the foods realize that some be eating ahead of time. This way, you might be stocked making use of necessary what you should cook and snack on. You should get regarding all the unhealthy foods in your house, and replace these people with healthy procedures. This way you won't have the temptations of seeing high calorie and fatty foods within your property.Think about being sleeker. Visualize clothes fitting better. Look at a favorite outfit or simply see yourself buying one or two sizes compact. Spend ten minutes each day exercising, choosing calorie free drinks, have never heard of weight loss supplement, and visualizing a slimmer body can boost weight-loss results.You could possibly be surprised of how much calories you took into the particular body by drinking up the said drinks, and discover seriously consider stopping if you really would like your new Landau scrub as well as your old Landau scrubs to match your figure eventually. On the other hand, there as well drinks that will help you lose dietary. Here are 3 drinks to assist you achieve that slimmer body you happen to be dreaming approximately.If you will not be familiar with martial arts you may be thinking; "Well why wouldn't he drop the sport if they have a black belt? Predicament is there to have an understanding of?" If that were the case, collisions were caused an excellent question, however in reality, achieving a black belt translates that one only has mastered methods of the art. When the attainment for a basic black belt, alternatives here . ten more degrees, or dans, that represent the technique to true mastery and lifelong study.
    Sep 23, 2018 64